Inhibin beta A drives colorectal cancer progression through macrophage M2 polarization and mitochondria-dependent ferroptosis suppression

#INHBA overexpression in #CRC drives #tumor growth by polarizing #macrophages to the M2 phenotype and suppressing mitochondrial #ferroptosis via SLC25A10 stabilization, highlighting INHBA as a target for combined immunoferroptosis therapeutic strategies.
#STTT: doi.org/10.1038/s413...

To characterize ovarian aging rates, we also devised a non-invasive blood-based #ovarian aging clock 🕐, based on a #RandomForest algorithm, which we call #OvAge. OvAge is derived from serum #AMH, #FSH and #INHBA, and is easily calculated using a shiny app:
minhooki.shinyapps.io/OvAge_Predic.... 4/9