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4/9 Pre-existing immunity from seasonal influenza exposure may protect against severe H5N1 illness. Cross-reactive antibodies against H5N1's neuraminidase can be found in humans, as current H1N1 viruses possess a related N1 neuraminidase.
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5/7 Some researchers offered more hope: immunologist Alessandro Sette noted that similarities between H5N1 and other flu viruses might provide some cross-reactive immunity for people previously exposed to similar strains, potentially moderating severity.
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