Using #CFDsimulations to reveal the mechanisms behind the initiation & progression of #AorticDissection, and identify hemodynamic-based metrics to assess progression risk in type B aortic #IntramuralHematoma patients. #medsky

Read: link.springer.com/article/10.1...

Global #GasderminD/GSDMD KO reduced #ThoracicAorticDissecition #IntramuralHematoma He in🐭+BAPN (0.2%) +locally applied Elastase

Which cell types in dissected🐭👤aortas undergo #Pyropotosis? #Inflammasome activity? Or GSDMD➡️other modes of death

bioRxiv 2024
www.biorxiv.org/content/10.1...