Low Selenium and Low Protein Exacerbate Myocardial Damage in Keshan Disease by Affecting the PINK1/Parkin-mediated Mitochondrial Autophagy Pathway

#Selenium and protein deficiency worsen #MyocardialInjury in #KeshanDisease by disrupting mitochondrial function and activating the #PINK1Parkin-mediated #mitophagy pathway, marked by elevated #CardiacInjury markers and altered #autophagy signaling.

#OpenAccess: doi.org/10.1007/s115...

This study reveals that low #Selenium and protein levels exacerbate #MyocardialInjury in #KeshanDisease by disrupting the PINK1/Parkin-mediated #Mitochondrial #Autophagy pathway, pointing to novel therapeutic strategies for intervention.

Read more: link.springer.com/article/10.1...