Using #KidneyOrganoids, this #STTT study shows that AAV transduction during #GeneTherapy promotes #Nephrotoxicity by inducing #Genotoxicity and IL-1β secretion, which activates the canonical NFκB pathway. #medsky @harvardmed.bsky.social
#OpenAccess: doi.org/10.1038/s413...
New webinar alert!
Join our upcoming workshop and optimize differentiation protocols and kidney organoid culturing.
📅Sep 23
🕓10 am CDT | 4 pm BST | 5 pm CEST
🔗Register now: ow.ly/7VEe50WPF6v
#Organoids #KidneyOrganoids #Culturing #Invitromodels #ProteintechEvents
🔎Check out the articles featured in the June KI
🔹 #Kidneyorganoids model transplant rejection
🔹 Piecing together a new kidney for #transplantation
🔹 Anti-nephrin antibodies in steroid-resistant
#nephroticsyndrome
⭐And more!
#NephSky #MedSky #SRNS
doi.org/10.1016/j.kint.2025.04.002
Starting to get very excited (and nervous!) for my talk at ISSCR in a few weeks! Presenting a short talk about our kidney assembloid protocol - check out our recent preprint for a sneak peek! doi.org/10.1101/2025... #ISSCR2025 #kidneyorganoids
📣 NEW PAPER ALERT! 🧵
I love kidney organoids - tiny nephron clusters grown in the lab from pluripotent stem cells. But can they treat kidney disease? New data suggests they can (in mice)!
Let's dive in ⬇️
tinyurl.com/mr3sd6vu
#KidneyOrganoids #CellTherapy #ChronicKidneyDisease #AcuteKidneyInjury
#Kidneyorganoids: a 3-dimensional tool to unmask permeability factors in primary and recurrent #FSGS
doi.org/10.1016/j.kint.2025.02.013
Original article: doi.org/10.1016/j.kint.2025.01.018
#KICommentary #MedSky #NephSky #focalsegmentalglomerulosclerosis
Challenges in maturation and integration of kidney organoids for stem cell–based renal replacement therapy
doi.org/10.1016/j.kint.2024.10.028
#KIMiniReview #OpenAccess #kidneyorganoids #transplantation
