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YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury - Genes & Immunity Genes & Immunity - YTHDF1 mediates KLF2/VSIG4 axis to regulate Kupffer cell polarization to alleviate sepsis-induced liver injury

๐Ÿ’ฅ #YTHDF1 mediates #KLF2/ #VSIG4 axis to regulate #Kupffer #cell #polarization to alleviate #sepsis-induced #liver #injury

#genes & #Immunity @springernature.com
www.nature.com/articles/s41...

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Congrats to our PIs @masslab.bsky.social & #HasenauerLab on their latest work uncovering the crosstalk between #Kupffer #Cells and #Hepatocytes in the context of maternal obesity.

A great example of macrophage-driven communication shaping tissue physiology
๐Ÿ‘‡ #Macrophages #Liver #Crosstalk

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TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV
TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV YouTube video by Gastroenterology at BMJ

Big thanks to the members of the @ihuhepatolyon.bsky.social, IP-cure-B ๐Ÿ‡ช๐Ÿ‡บ and Gut for the opportunity to share our work. Barbara Testoni, Fabien Zoulim, Marie-Laure Plissonnier. #HBV #Kupffer #Liver
youtu.be/rhxBiquxHfU?...

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@haohuang0086.bsky.social presenting our maternal obesity @ #EMDS !! Check out also our poster about the role of microplastics in #Kupffer cells by @mariafviola.bsky.social

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