Epigentics Update - LSD1 inhibition ameliorates congenital dyserythropoietic anemia type II bit.ly/4srzOzk
Lei Yu and Rami Khoriaty @umich.edu in Sci Trans Med
#Epigenetics #LSD1 #HistoneDemethylation #Anemia #CDAII
---
Perfect for cancer, immunology, and aging research; epigenometech.com
Featured in IJOS's [Top 5 Articles in the first half of 2025]🥳：LSD1 is a protein that promotes cancer. Recent study shows inhibiting LSD1 can reverse early cancer changes and boost immune response, offering a new strategy for oral cancer treatment！👍
#LSD1 #cancer
www.nature.com/articles/s41...
Earlier this year we uncovered 🧠 neuron-specific splicing events for 14 chromatin regulators 🧬 including H3K4 demethylase #LSD1 and reader #PHF21A. Alternative splicing of ubiquitously-expressed chromatin regulators, therefore, can exert neuron-specific function.
New app note! 📄
Working with a key intermediate from the Harvard Liau Group, we achieved high-throughput chiral separation using CHIRALPAK® IK—100 mg/hr on a 4.6 mm column.
🔗 chiraltech.com/wp-content/u...
#ChiralSeparation #LSD1 #CancerResearch #Harvard #HPLC #DrugDiscovery
A study published in International Journal of Oral Science (2025) on April 17, 2025, uncovers the pivotal role of LSD1 in the progression of oral cancer.
#cancer #LSD1
Details: doi.org/10.1038/s413...
This extensive review explores the structural features, #posttranslationalmodifications, and disease-related roles of #LSD1 and provides valuable insights into the potential therapeutic implications of targeting LSD1 and its modifications in various diseases. #medsky
#OpenAccess: buff.ly/tMPQBLy
