🚨 New pre-print from the #MAGICproject!

Our team modelled L-CMD, a severe laminopathy, using iPSC-derived skeletal muscle & showed how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.

biorxiv.org/content/10.1...

#Laminopathy #GeneTherapy #iPSC

🚨 New pre-print from the #MAGICproject!

We model L-CMD-a severe laminopathy-using iPSC-derived skeletal muscle & show how precise CRISPR correction reverses nuclear defects, while exon-skipping doesn’t.

www.biorxiv.org/content/10.1...
#Laminopathy #GeneTherapy #iPSC

Day 2 of the #Laminopathies conference is underway! 💡 Dive into today’s sessions and connect with the global community driving progress in laminopathy research. Full program available at laminopathies.net

#RareDisease #Laminopathy #Laminopathies

An unforgettable evening at the #Laminopathies conference gala dinner/cocktail party - great conversations, inspiring connections, and a stunning venue. Huge thanks to the organisers and @LmnaCardiac for bringing this community together! 💙 #RareDisease #Laminopathy #lmnacardiac

Roles of the lamin A-specific tail region in the localization to sites of nuclear envelope rupture Abstract. The nuclear lamina (NL) lines the nuclear envelope (NE) to maintain nuclear structure in metazoan cells. The major NL components, the nuclear lam

Roles of the #Lamin A-specific Tail Region in the Localization to Sites of Nuclear Envelope Rupture @PNASNexus.org
@sciencetokyo.bsky.social #KanazawaUniv #NanoLSI
#Progeria #HGPS #RareDisease #Lonafarnib #Zokinvy #Laminopathy #cardiomyopathy #lipodystrophy #LMNA academic.oup.com/pnasnexus/ar...