🔆 #PaperSpotlight:
A new #research paper was #published on August 27, titled “Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis.”

🔗 doi.org/10.18632/agi...

#aging #quote #progeria #HGPS #adipogenesis #openaccess #journal #publishing #meded

#HGPS #Aortopathy

The age-related accumulation of immature Lamin A, #Progerin or Farnesyl-Prelamin A, ⏫Stretch-induced loss of aortic #SmoothMuscleCell

Comparative analysis among
1⃣LmnaG609G/+
2⃣Zmpste24-/-
3⃣SM22a-Cre::Zmpste f/f::LmnaPLAO/PLAO🐭

#CellDeathDis 2025
www.nature.com/articles/s41...

Phase behavior and dissociation kinetics of lamins in a polymer model of progeria One of the key structural proteins in the eukaryotic cell nucleus is lamin. Lamins can assemble into a two-dimensional protein meshwork at the nuclear periphery

Read more 👉 pubs.aip.org/aip/jcp/arti...
#CellBiology #Laminopathies #HGPS #NuclearMechanics #Research #Biophysics

Roles of the lamin A-specific tail region in the localization to sites of nuclear envelope rupture Abstract. The nuclear lamina (NL) lines the nuclear envelope (NE) to maintain nuclear structure in metazoan cells. The major NL components, the nuclear lam

Roles of the #Lamin A-specific Tail Region in the Localization to Sites of Nuclear Envelope Rupture @PNASNexus.org
@sciencetokyo.bsky.social #KanazawaUniv #NanoLSI
#Progeria #HGPS #RareDisease #Lonafarnib #Zokinvy #Laminopathy #cardiomyopathy #lipodystrophy #LMNA academic.oup.com/pnasnexus/ar...