📄 Hong et al. J Hematol Oncol 2026 — BCMA-CD19
"armored" CAR T in SLE

LLCPsはその"見えにくさ"から, 既存の治療ではSLEのはじめとした自己抗体が関連する複数の疾患において再燃に関与することが示唆されている.
この研究はCD19とBCMAを二重標的とするCARTがLLPCsを含むより"深い"寛解を達成する可能性を示しており, また患者が正常妊娠を達成するという望外の結果も得られている.

12人と限られた研究ではあるが, そのインパクトは無視できない

#NephSky #CART #LupusNephritis

Systematic Review of #TrialDesign and #Endpoints in #LupusNephritis

#VisualAbstract by @RafaelLpezMrqu2

www.kireports.org/article/S2468-0249(26)02...

Gut microbe R. gnavus could be key to lupus, lupus nephritis pathogenesis A bacteria found in the gut may “very important” to the development of lupus and lupus nephritis, according to a speaker at the Basic and Clinical Immunology for the Busy Clinician symposium.“We have…

"Rheuminococcus gnavus #bacteria may be associated with #lupus and #LupusNephritis. Treating R. gnavus could limit the need for #biologic or DMARD therapy in some patients with lupus.": buff.ly/3i05kAX

via @gohealio.bsky.social
#MedicalResearch #GutMicrobe #autoimmune #ChronicIllness

As #NationalKidneyMonth comes to a close, kidney health matters all year long 💜 For people living with #lupus, understanding #lupusnephritis & knowing when to get screened can make a difference.

Learn more about symptoms, testing, & treatment options: buff.ly/DubOrPM

#Lupusnephritis may not show symptoms right away. That’s why understanding kidney health is an important part of living with #lupus.

Learn how lupus affects the kidneys, signs to watch for, testing options, and treatments in our resource: buff.ly/Gz0o5Dg

What if diagnosing #lupusnephritis didn't require a kidney biopsy?

This #NationalKidneyMonth, learn how Dr. Fava from John Hopkins Medicine and recipient of LFA's Career Development Award is bringing earlier answers & better outcomes.

Learn more: buff.ly/ERVnXs3

You don't have to do this alone. 💜

This #KidneyMonth, meet Raena — diagnosed with #lupusnephritis at 21 and now a co-facilitator of LFA's National #Lupus Kidney Care support group.

Free. Virtual. Open to all. Find your community and join today: buff.ly/YDxFZjG

Excited to see ‘UK Kidney Week’ coming back to Wales in 2027 👏🏻🦋 #lupusnephritis

Gut microbe R. gnavus could be key to lupus, lupus nephritis pathogenesis A bacteria found in the gut may “very important” to the development of lupus and lupus nephritis, according to a speaker at the Basic and Clinical Immunology for the Busy Clinician symposium.“We have…

"“As the severity of the disease [ #Lupus / #LupusNephritis ] increased, the prevalence of this #bacteria [Rheuminococcus gnavus] increased,” he said. “Correlation is not causation, but this bacteria is very important.”": buff.ly/3i05kAX

via @gohealio.bsky.social
#MedSky #GutHealth #rheumatology

New insights in lupus care are emerging, from better monitoring to more patient-centered treatment decisions. Learn what patients and providers should know about lupus nephritis and why early action matters.

➡️ Read more: zurl.co/NJCn9 💜

#AiArthritis #Lupus #LupusNephritis #SLE #LupusAwareness

Research Article

The Renal Activity Index for Lupus: Validation for Prediction of Kidney Inflammation in Adult Patients With Lupus Nephritis

📖 doi.org/10.3899/jrhe...

#Biomarkers #LupusNephritis #Lupus

#FactFriday 💜 #Lupusnephritis is a serious complication of #lupus that can quietly affect kidney health over time. Understanding how lupus impacts the kidneys—and why early screening matters—can help people advocate for their care sooner.

Learn more: buff.ly/L6yQBi4

#NationalKidneyMonth

Read our latest issue: https://bit.ly/4l3G51a

#Gonorrhea #EosinophilicAsthma #LupusNephritis #HeartFailure #AML

💜 Meet Timeka. Diagnosed with #lupusnephritis, she was terrified—but through the Lupus Foundation of America, she found answers, specialists, and a community that reminded her she wasn’t alone.

Support people with #lupus and give today: buff.ly/mXQpR0p

#KidneyMonth

March marks the start of #NationalKidneyMonth 💜 DYK #lupusnephritis affects up to 60% of people with #lupus, often within the first five years of diagnosis.

Learn the signs, screening, and treatment options in our Lupus Nephritis Information Center: buff.ly/fNm1NnC

National Kidney Month

National Kidney Month, for us humans as well as for our cats. I´m a longtime #SLE survivor, thank God I do not have #LupusNephritis so far. 80 % of the patients get it sooner or later...
www.kidney.org/national-kid...
From my @blindcatrescue.bsky.social newsletter.

Have you failed at least 2 therapies for your lupus nephritis? If so, you might be eligible to take part in the Frontier Study. Learn more at https://app.patientwing.com/campaign/ANRF-AB to see high level info about the study and potential next steps.

#LupusNephritis #PartnerPost #ClinicalTrial

NICE backs Roche lupus drug that supports kidney function Roche's Gazyvaro, a drug that can restore kidney function in lupus nephritis, has been cleared for use by the NHS in England and Wales.

#NICE #Roche #lupusdrug #lupus #lupusnephritis #systemiclupuserythematosus #SLE #kidneyfunction #Gazyvaro #obinutuzumab #NHS #kidneydisease #autoimmunedisorder #antiCD20antibody #NICEdraftrecommendation #Clinicaltrials #MMF #phase3clinicaltrial #ALLEGORYtrial #LupusUK #HEOR
zurl.co/cH0ta

Do you or a loved one have treatment-resistant lupus nephritis? You can visit this website to explore information about a clinical study and submit a short questionnaire to see if you are eligible: https://app.patientwing.com/campaign/ANRF-AB

#LupusNephritis #PartnerPost #ClinicalTrial

Evaluating #Chronicity Scores for Outcomes in #LupusNephritis Patients

#VisualAbstract by Kajaree

www.kireports.org/article/S2468-0249(26)00...

Thousands living with lupus offered hope from twice-yearly infusion Sign up for our newsletters and alerts

“[ #Obinutuzumab (Gazyvaro)] has been approved for #NHS use, offering new hope to the nearly 12,000 people in England living with #LupusNephritis.”: buff.ly/chsHoqF

from @NICEComms.bsky.social
#lupus #rheumatology #MedSky #autoimmune

NICE have recommended that a new treatment, obinutuzumab, can be used in combination with mycophenolate mofetil (MMF) to treat some patients with lupus nephritis in the NHS in England and Wales. 

👉 Learn more at https://lupusuk.org.uk/latest-news/

#Lupus #LupusNephritis #Obinutuzumab

#Roche's #Gazyvaro, a drug that can restore #kidneyfunction in people living with #lupusnephritis, has been cleared for use by the #NHS in England and Wales.

pharmaphorum.com/news/nice-ba...

Mesenchymal stem cell–mediated renal remodeling in lupus nephritis
MSCs reshape renal inflammation via CXCL10-CXCR3 recruitment and IL4I1 signaling in lupus nephritis.
www.nature.com/articles/s41...
#MesenchymalStemCells #LupusNephritis #RenalDisease #Immunomodulation

Meet Anthony. Diagnosed with #lupusnephritis at 19. Standing with #lupus warriors, he saw the power of advocacy when we come together. 📣 Registration for the LFA's National #LupusAdvocacy Summit is open. Join us in DC on 4/20-21.

Save your spot today: buff.ly/LYWn0Vy

Renal #Response Status and Long-Term Kidney #Outcomes in #Childhood-Onset #LupusNephritis

#VisualAbstract by Priya John

www.kireports.org/article/S2468-0249(25)00...

2 years after @lupusuk.bsky.social ´s been founded in 1990, in 1992, my #SLE broke out, but it hasn´t been diagnosed before 08/02. So far #LupusNephritis spared me, but I belong to those who´re chronic underweight from #Lupus. I´m almost 55.
www.youtube.com/watch?v=F432...

Characterizing the #NIH #Activity and #Chronicity Indices in 2 Independent #LupusNephritis Cohorts

#VisualAbstract by Denisse Arellano

www.kireports.org/article/S2468-0249(25)00...

Glomerular endothelial cells eliminate nicotinamide adenine dinucleotide to instruct CD103+ T cells in human lupus nephritis.
Cao, Qinghua et al.
Paper
Details
#LupusNephritis #GlomerularEndothelialCells #CD103Tcells

Inactive lupus nephritis & SGLT2i data: NDT cross-over trial (n=30). Dapagliflozin + standard care vs usual therapy for 6 mo; 9 excluded (flare/LTFU). Proteinuria ↓ –36.1% vs –3.5%. More hypotension symptoms; no sig BP/weight changes. #LupusNephritis
🔗 doi.org/10.1093/ndt/...