MGR’s contribution to TN’s progress outstanding, says PM Modi on his birth anniversary Chennai, Jan 17 (SocialNews.XYZ) On the birth anniversary of legendary actor, philanthropist, and former Chief Minister M. G. Ramachandran, Prime Minister Narendra Modi on Saturday paid glowing tributes, recalling MGR as a towering personality whose life and work left an indelible imprint on Tamil Nadu and Tamil society at large. PM Modi in his post on X said, "Paying homage to the exceptional MGR on his Jayanti.

MGR's contribution to TN's progress outstanding, says PM Modi on his birth anniversary #MGRs #TNs #PMModi #socialnewsxyz

Kappa-type light chain proximal tubulopathy
On EM, low mag shows membrane-bound crystalline-like cytoplasmic inclusions but up close has fibrillar appearance.
🔹Congo-red is negative
🔹Reported w/ MGUS, MM, & lymphoma
🔹Most had fanconi syndrome
#MGRS #renalpath #pathsky #nephsky #nephrology
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Is the #Mayo prediction tool for #MGRS ready for prime time?
Commentary by Jack Wetzels
doi.org/10.1016/j.kint.2025.05.010

Original article: doi.org/10.1016/j.kint.2025.04.018

#MedSky #NephSky #kidneybiopsy #renalbiopsy #pathsky #CKD #chronickidneydisease #KICommentary

🔍Proteinuria in monoclonal gammopathy? Don’t miss the diagnostic clues!

🚰uAPR < 40%? Think tubular
🧪uAPR > 40%? Glomerular path ahead

From cast nephropathy to MGRS, biopsy is 🔑

📉LC ≤10%= cast nephropathy
📊LC >10%= #LCPT

🧬 #MGRS = Biopsy it

🔗 doi.org/10.1016/j.lp...

#NephSky #MGRS #MM #Medsky

[8/10] L’exclusivité des brevets peut freiner l’accès des pays du Sud aux résultats issus des #MGRs. Les auteurs suggèrent de restreindre juridiquement cette exclusivité dans les domaines d’intérêt public (santé, environnement), notamment via des exceptions au sein de l’OMC. #HGGSP #geography

[7/10] Le partage des bénéfices peut être monétaire ou non monétaire. Dans le cas des #MGRs en haute mer, les auteurs plaident pour des formes non monétaires (transfert de technologie, accès aux données, coopération scientifique), plus réalisables et moins conflictuelles. #HGGSP #geography

[6/10] Le droit de la propriété intellectuelle accorde un monopole temporaire sur les informations issues des #MGRs, mais pas sur les ressources elles-mêmes. Ce mécanisme d’incitation à l’innovation est compatible avec l’idée d’un partage non exclusif des bénéfices. #HGGSP #geography

[5/10] Les #MGRs in ABNJ nécessitent des technologies complexes (génomique, biotechnologie) pour libérer leur potentiel. Leurs applications médicales ou industrielles sont très prometteuses mais leur développmt exige des investissements élevés justifiant un cadre juridique stable. #HGGSP #geography

[4/10] L’accord #BBNJ n’a pas tranché ce débat : il reconnaît l’« héritage commun de l’humanité » comme principe, sans l’appliquer directement aux #MGRs. Ce compromis reflète une tension Nord-Sud sur l’exploitation des ressources naturelles mondiales. #HGGSP #geography

Nephrology Grand Rounds with Kara Cicero, MD, MPH - "Monoclonal Gammopathy and #Renal Insufficiency: Red Herring or #MGRS?" #kidney #nephsky
@uwmedicine.bsky.social
Watch: youtu.be/fm6to5rEctc

Monoclonal Gammopathy of Renal Significance (MGRS): Overview, Diagnosis, and Management
#DVP183
#MGRS #KidneyDisease #Nephrology #Amyloidosis #VikaasLLC #LCDD #KidneyBiopsy #Bortezomib #Rituximab #Daratumumab #MGUS #Myeloma #Proteinuria #ESKD

GridScout Map™ Pursuit of proficiency in the manly arts, like maps and knots and locks and guns.

The new-fangled bulk map-search tool that you didn’t know you needed, featuring #MGRS coordinates and cutting-edge integration with old-fashioned paper maps! ;-}

www.gridscout.net

The Mayo #MGRS Prediction Tool calculates the risk of finding monoclonal gammopathy of renal significance in a #kidneybiopsy in patients with #monoclonalgammopathy

doi.org/10.1016/j.kint.2025.04.018

#NephSky #MedSky #renalbiopsy @mayoclinic.org

🤔Ever seen IgG3 act this wild in the kidney?🫘

🔬PGNMID = mysterious monoclonal Ig with renal-limited fury

🧩Pathophys still unclear but beautifully illustrated here👇

📖Bridoux et al @ndt-era.bsky.social

🔗 doi.org/10.1093/ndt/...

#Nephrology #MGRS #PGNMID #MedTwitter #RenalPath #NephTwitter

Sending an absolute metric ton of love to @jenlosi.bsky.social (and also to the glorious #BillMillsap and team over at #MGRS) for including me in this project… it came at a time I was doubting my abilities as a trans actor, and you gave me strength and made me feel worthy of this walk. Thank you. 🩵

Diffuse linear staining along GBMs, mesangium, Bowman's capsule, TBMs, and vascular basement membranes.

punctate powdery granular deposits in tubular basement membranes and lamina rara internal of GBMs

Nodular glomerulosclerosis & PAS-positive deposits staining basement membranes and vessel wall intima & surrounding medial myocytes

Light chain deposition disease (LCDD), kappa type.
Kappa represents 80-90% of LCDD
*IF: intense linear LC-restricted stain of basement membranes
*EM: punctate powdery deposits
*nodular diabetes-like GS
*PAS+ deposits in nodules, TBM & surrounds medial myocytes
#renalpath #nephsky #pathsky #MGRS

My #ASH24 highlights from yesterday were the talks that emphasised the importance of increasing awareness of #MGUS, monoclonal gammopathies of clinical significance like #MGRS and #MGNS, and #ALAmyloidosis so patients can be diagnosed earlier.

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Додаток TacticMap для всіх військових та цивільних на iPhone
apps.apple.com/ua/app/tacti...

#TacticMap #Apple #iPad #iPhone #Ukraine #Navigation #Map #NATO #MGRS #UTM #AppStore

What is WGS84 – An Overview The World Geodetic System 1984 (WGS 84) is a geodetic reference system used to describe the shape and size of the Earth. We will delve into its historical context, technical specifications, global …

Something of personal interest is the #WGS84 coordinate system. This is the base for most electronic #navigation and #coordinate systems like #UTM #MGRS #ECEF and much more svenruppert.com/2023/12/18/w...

New stuff on #MGRS and PGNMID www.kireports.org/article/S2468-0249(23)01... @KIReports @nymurakami

Heme Grand Rounds @kdjhaveri #onconephrology on #myeloma kidney, #PGNMID, #MGRS @HofNorthwellDOM

jasn.asnjournals.org/content/early/2020/07/31... this study is amazing. For the first time we have an incidence of #mgrs @LadanZand @JASN_News

#onconephrology #clinicalpearl: AL amyloidosis, the most common end organ damage is in the kidney--although a form of #MGRS, majority patients do not meet diagnostic criteria for multiple myeloma. It is the oldest MGRS disease we have known....

PageNotFound - Penn Medicine

Faculty Profile for @ASNKidney #onconephrology course John Hogan @PennKidney on paraproteinemias #MGRS www.pennmedicine.org/providers/profile/jonath... #kidneywk 2019

#MGRS related renal lesions being presented by @jradnephro

@kdjhaveri presenting #MGRS

What you need to know re: #MGRS or #paraprotein disease in the #kidney by @VBijol

#MGRS @AJurczyszyn @goKDIGO #KDIGOOnconeph

#MGRS @AJurczyszyn @goKDIGO #KDIGOOnconeph

Treatment options of #MGRS @AJurczyszyn @goKDIGO #KDIGOOnconeph