This is the C4d immunofluorescence from a 5y post-transplant biopsy of an AA female who had ESRD due to lupus nephritis. What is your diagnosis?
#DiagnoseThis #nephsky #pathsky #renal #kidneypath
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However, new research shows the picture is more nuanced than we thought. Not everyone with two copies develops disease, and we've discovered a protective modifier variant called M1 that can lower risk when it's inherited with the G2 variant. #apol1 #renal
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A sample from the pathology teaching slide set on Membranous Glomerulopathy:
PLA2R Testing and When to Consider Kidney Biopsy, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath
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Analysis of the interplay between #uromodulin excretion and #water balance in a healthy adult population reports associations with #urine volume, urine #osmolality and #copeptin levels.
doi.org/10.14814/phy...
#Renal
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1/ The image shows global endocapillary hypercellularity with numerous neutrophils (exsudative glomerulonephritis). The patient was found to have tricuspid valve endocarditis.
#renalpath #kidneypath #pathology #renal
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Here is today’s #eyeSCANdy! Scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial loss of interdigitating podocyte foot processes.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
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This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for significant glomerular or tubulointerstitial immune complex deposits.
#TeachingPoints #kidneypath #renal #pathology
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In a patient who is IV drug user and IF showing C3 only staining, what is your diagnosis?
#DiagnoseThis #nephtwitter #pathtwitter #renal #kidneypath
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More research is needed regarding the suspected link between feline #vaccines & feline chronic kidney disease. 😿
#cats #kittens #CKD #kidneys #renal #vetmed #vetsky #veterinary #caregivers #veterinarymedicine
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A sample from the pathology teaching slide set on IgA Nephropathy, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath
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#cats #catsky #CatsOfBlueSky #CKD #kidneys #renal #healthcare #caregivers #pets #veterinary #vetmed #vetsky #vermedsky #veterinarymedicine #pharmacy #pharmacies #medication
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Here is today’s #eyeSCANdy! Scanning EM of a normal glomerulus showing a glomerular capillary loop with interdigitating podocyte foot processes.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
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Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions.
#TeachingPoints #kidneypath #renal #pathology
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This is an IgG IF viewed under both fluorescent and polarized light from a patient with AKI following endovascular procedure. What is your diagnosis?
#DiagnoseThis #nephtwitter #pathtwitter #renal #kidneypath
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Caregivers shouldn't HAVE to ask the vet to check their pets' blood pressure. That should be a routine part of every physical exam, just like it is for humans. 🤨 #vetmed #vetsky #veterinary #veterinarymedicine #cats #CKD #hypertension #kidneys #renal #BP
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A sample from the pathology teaching slide set on Membranous Glomerulopathy, jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath
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REMIND YOUR CLIENTS. Lilies DON'T BELONG in a house where cats live. Even the POLLEN can kill.
#cats #kittens #catsky #CatsOfBlueSky #lilies #toxic #Easter #spring #kidneys #renal #danger #vetmed #vetsky #veterinary
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Here is today’s #eyeSCANdy! Scanning EM of a normal glomerulus showing a glomerular capillary loop with interdigitating podocyte foot processes.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
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Outcomes of complete responders from first-line therapy in metastatic #renal cell #carcinoma in the real world: an analysis from the International Metastatic Renal Cell Carcinoma Database Consortium www.sciencedirect.com/science/arti... #hvhebron #onco [Text complet]
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This is a CMV IHC stain, showing CMV positive cells within glomeruli. CMV viral load was four million copies/ml, and bilateral CMV pneumonia was diagnosed.
#renalpath #kidneypath #pathology #renal
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UPFRONT Mystery Case #50: Screening Eye Exam in a 9-Year-Old Female with Congenital Renal Dysplasia: Journal of Neuro-Ophthalmology
Article: bit.ly/JNO_renal_dy... or on bit.ly/JNO_Home#brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #renal @BostonChildrens @harvardmed
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As published decades ago by Bonsib et al. (see reference), fluorescence microscopy of eosin-stained frozen section slides can be a valuable tool in providing diagnostic clues in kidney biopsies.
#TeachingPoints #kidneypath #renal #pathology
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32 yo renal transplant recipient with AKI and pneumonia. A recent biopsy had shown borderline changes for TCMR and the patient received pulse steroids.
#DiagnoseThis #nephtwitter #pathtwitter #renal #kidneypath
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Sometimes the giant cells in granulomatous inflammation are truly giant!
#nephsky #pathsky #renal #kidneypath
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#cats #catsky #CatsOfBlueSky #vetmed #veterinary #veterinarymedicine #vetsky #CKD #kidneys #renal #health #resources #caregivers
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A sample from the pathology teaching slide set on Lupus Nephritis and Thrombotic Microangiopathy (TMA), jointly prepared by Arkana Laboratories and @goKDIGO. http://KDIGO.org/guidelines/gd/
#KDIGO #pathology #renal #kidneypath
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Here is today’s #eyeSCANdy! Scanning EM of a normal glomerulus showing a glomerular capillary loop with interdigitating podocyte foot processes.
Photo courtesy of Dr. Stephen Bonsib. #renal #pathology #kidneypath
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There were also mesangial IgA deposits (Figure 3), which likely explain the patient's hematuria and proteinuria, since there was very little glomerular amyloid (Figure 4).
#renalpath #kidneypath #pathology #renal #pathsky
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The stain is a Congo Red viewed under fluorescent light with a red filter. It highlights interstitial amyloid deposits, which is the predominant pattern of deposition in LECT2 amyloidosis (confirmed by IHC stain, Figure 2).
#renalpath #kidneypath #pathology #renal #pathsky
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