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🔷 Secondary outcomes included testosterone suppression, overall survival, and safety, with tE2 showing similar castration rates and fewer hot flashes but higher gynecomastia, supporting its potential as an alternative hormonal therapy option.
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Preliminary Safety and Efficacy of Navitoclax Plus Ruxolitinib in Janus Kinase Inhibitor-Naïve Patients With Myelofibrosis From the Multicenter, Open-Label, Phase 2 Study (REFINE) onlinelibrary.wiley.com/doi/10.1002/... #hvhebron #onco [Text complet]
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Cabozantinib versus placebo in patients with radioiodine-refractory differentiated thyroid cancer after prior vascular endothelial growth factor receptor-targeted therapy (COSMIC-311): outcomes by BRAF status www.frontiersin.org/journals/onc... #hvhebron #onco [Text complet] @frontiersin.bsky.social
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CALYPSO: Final Results of Savolitinib and Durvalumab Combination in Metastatic Papillary Renal Cancer ascopubs.org/doi/10.1200/... #hvhebron #onco
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Photocaged Chloroquine Derivatives for the Light-Dependent Inhibition of Autophagy in Cancer Stem Cells pubs.acs.org/doi/10.1021/... #hvhebron #bio #cibbim #onco [Text complet] @pubs.acs.org
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Epithelioid sarcoma: from SMARCB1 loss to therapeutic vulnerabilities journals.lww.com/co-oncology/... #hvhebron #onco
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Imlunestrant with or without abemaciclib in advanced breast cancer: updated efficacy results from the phase III EMBER-3 trial www.annalsofoncology.org/article/S092... #hvhebron #onco [Text complet]
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Datopotamab Deruxtecan Plus Pembrolizumab With or Without Platinum-Based Chemotherapy for Advanced or Metastatic NSCLC: The Phase Ib TROPION-Lung02 Trial www.jto.org/article/S155... #hvhebron #onco
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Second-line liposomal irinotecan plus S-1 vs. liposomal irinotecan plus 5-fluorouracil in metastatic pancreatic cancer: the phase I/II randomized NAPAN trial www.sciencedirect.com/science/arti... #hvhebron #onco
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#ONCO Onconetix, Inc. Announces 1-for-5 Reverse Stock Split
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Inactivation of CDKN2AARF Promotes p53-Independent Remodeling of the PDAC Tumor Microenvironment aacrjournals.org/cancerres/ar... #hvhebron #onco
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miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis www.science.org/doi/10.1126/... #hvhebron #onco [Text complet] @science.org
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Safety and Efficacy of Epirubicin, Ifosfamide, and Nivolumab as First-line treatment for patients with Undifferentiated Pleomorphic Sarcoma aacrjournals.org/clincancerre... #hvhebron #onco @aacrjournals.bsky.social
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Clinical experience and satisfaction in patients with advanced breast cancer participating in the abemaciclib patient support program in Spain: a prospective observational study link.springer.com/article/10.1... #hvhebron #onco [Text complet]
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Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer jitc.bmj.com/content/14/3... #hvhebron #onco [Text complet]
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Quantitative HER2 tissue and plasma profiling predicts the activity of trastuzumab deruxtecan for breast cancer www.nature.com/articles/s41... #hvhebron #onco [Text complet]
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IMMUNOSARC II Master Trial: Phase II Study of Sunitinib and Nivolumab in Clear Cell Sarcoma Cohort spj.science.org/doi/10.34133... #hvhebron #onco #ap [Text complet]
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A CDCA2-MYC positive feedback loop controls cancer cells survival royalsocietypublishing.org/rsob/article... #hvhebron #onco [Text complet] @royalsocietypublishing.org
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Outcomes of complete responders from first-line therapy in metastatic #renal cell #carcinoma in the real world: an analysis from the International Metastatic Renal Cell Carcinoma Database Consortium www.sciencedirect.com/science/arti... #hvhebron #onco [Text complet]
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Phase III trial of infigratinib versus gemcitabine/cisplatin in adults with advanced cholangiocarcinoma with FGFR2 gene fusion or rearrangement: results and reflections on early termination of PROOF 301 www.sciencedirect.com/science/arti... #hvhebron #onco [Text complet]
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Combined Serum (1,3)-β-D-Glucan and Oral Wash PCR as a Noninvasive Diagnostic Strategy for Early Detection of Pneumocystis jirovecii #Pneumonia academic.oup.com/ofid/article... #hvhebron #onco #medint #hemat #malinf #micro #mintens #pneu [Text complet] @ofidjournal.bsky.social
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Beamion PANTUMOR-1: rationale and design of a Phase II trial of zongertinib in HER2-overexpressed/amplified or HER2-mutant solid #tumors www.tandfonline.com/doi/full/10.... #hvhebron #onco
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Homologous recombination deficiency and hemizygosity drive resistance in #breast #cancer www.nature.com/articles/s41... #hvhebron #onco [Text complet]
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RAD51-based homologous recombination deficiency is associated with treatment response and survival in early #breast #cancer www.nature.com/articles/s41... #hvhebron #onco [Text complet]
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First-in-human phase 1 study of RO7119929, an oral TLR7 agonist prodrug, in patients with advanced primary or metastatic #liver #cancers jitc.bmj.com/content/14/3... #hvhebron #onco [Text complet]
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Real-world evidence for the use of olaparib in #pancreatic #cancer in Spanish hospitals www.tandfonline.com/doi/full/10.... #hvhebron #far #onco
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Decoding B Cell Signatures of Complete Pathological Response to Perioperative Chemoimmunotherapy in Non-Small Cell Lung #Cancer aacrjournals.org/clincancerre... #hvhebron #onco [Text complet] @aacrjournals.bsky.social
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