Enterococcus faecalis: an overlooked cell invader | Microbiology and Molecular Biology Reviews SUMMARYEnterococcus faecalis and Enterococcus faecium are human pathobionts that exhibit a dual lifestyle as commensal and pathogenic bacteria. The pathogenic lifestyle is associated with specific conditions involving host susceptibility and intestinal ...

🧵Enterococcus faecalis is not just an extracellular organism. 🧵 A growing body of work shows it can survive + REPLICATE inside host cells, and that intracellular life may seed persistence, dissemination, and reinfection. 1/n #MMBR @asm.org journals.asm.org/doi/10.1128/...

Examples of protein annotations across functional classification schemes. Yellow: hierarchical classification schemes, red: orthologous/homologous groups, and blue: methods using protein domain information. Protein structures were generated using the ColabFold Alphafold MMseqs2 interactive notebook (version 1.5.2) (57) and visualized using ChimeraX (58). (A) Functional labels associated with the glycogen synthase protein in Escherichia coli (UniprotKB P0A6U8). (B) Functional labels associated with Kehishuvirus sp. tikala major capsid protein (NCBI WEU69752.1).

New in @asm.org #MMBR Computational function prediction of bacteria and phage proteins. How to annotate your #phage and #bacteria genomes

by @susiegriggo.bsky.social @bedutilh.bsky.social @gbouras13.bsky.social and Bob

#phagesky #microsky

journals.asm.org/doi/epub/10....

Computational function prediction of bacteria and phage proteins | Microbiology and Molecular Biology Reviews SUMMARYUnderstanding protein functions is crucial for interpreting microbial life; however, reliable function annotation remains a major challenge in computational biology. Despite significant advance...

Thrilled to share our new review just published in Microbiology and Molecular Biology Reviews (@asm.org #MMBR):
“Computational Function Prediction of Bacteria and Phage Proteins”
with @gbouras13.bsky.social @linsalrob.bsky.social @bedutilh.bsky.social
🔗 journals.asm.org/doi/10.1128/...

Overview of variation in microbial vitamin biosynthesis throughout human lifespan. Panel (a) shows the relative abundance of global and individual vitamin biosynthetic pathways in the gut microbiota of infants, adults, and the elderly, highlighting marked age-associated differences. The phylogenetic tree on panel (b) depicts the distribution of vitamin biosynthetic potential across key bacterial genera of the infant gut microbiota.

Did you know gut bacteria make vitamins? 🦠💊In #MMBR, discover mechanisms of microbiota vitamin biosynthesis, how interactions between microbiota members contribute to vitamin production, the role of diet and more. Read the review: asm.social/2mF

The fibrillar ECM of developing E. faecalis biofilms contains DNA (reproduced from reference 148). A 4 h biofilm developing on a fluoropolymer (Aclar) coupon was prepared with labeling with a gold-labeled anti-DNA monoclonal antibody. Scale bar = 0.5 µm.

#MicrobiologyMonday: The "robustness" of enterococci is tied to biofilm formation. The ability to study the genetic underpinnings of biofilms formed by enterococci & other bacteria has grown, which improves understanding of their form & function. Learn more in #MMBR: journals.asm.org/doi/10.1128/...

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Hill and Gilbert mine human-associated Built Environment research to suggest how future work on the microbial ecology of animal-built natural nests and burrows, as well as artificial enclosures could be explored. #MMBR #ASMicro doi.org/10.1128/mmbr...

Just posted, Mazel et al. on how aminoglycosides, a critical class of antibiotics, function, interact with other antibiotics, and stress out Gram-negative bacteria #mmbr #ASMicro
doi-org.colorado.idm.oclc.org/10.1128/mmbr... @amazeld.bsky.social