What are germline mutations and what role do they play in hereditary cancer?
The infographic can be downloaded at: genetionary.org/resources/
#HereditaryCancerWeek #GermlineMutations #Cancer #GeneticTesting #LynchSyndrome #BRCA2 #BRCA1 #CHEK2 #ATM #PALB2 #PTEN #MLH1 #MSH2 #MSH6 #TP53 #DNA
A study found that cancer was commonly found in #MSH6 & #PMS2 carriers even under age 30. Recommendations suggest delaying colonoscopy until age 30 in these carriers, thus study authors suggest this may lead to missed opportunities for preventing cancer. Learn more: pubmed.ncbi.nlm.nih.gov/40013688/
March 22nd is #๐๐๐ป๐ฐ๐ต๐ฆ๐๐ป๐ฑ๐ฟ๐ผ๐บ๐ฒ๐๐๐ฎ๐ฟ๐ฒ๐ป๐ฒ๐๐๐๐ฎ๐! Lynch Syndrome is due to inherited mutations in #MLH1, #MSH2, #MSH6, #PMS2, and #EPCAM. Did you know that 1 in 279 individuals have #LynchSyndrome, yet only 5% know they are positive for #LynchSyndrome?
