#Heterochromatin #Mechanobiolgy

Pulsatile #LaminarShearStress➡️ sustained ⏫SUV39H1 (histone methyltransferase) & H3K9me3 at inflammatory genes (SELE VCAM1) in #EndothelialCell

SUV39H1 physically interacts with Emerin➡️⏫H3K9me3 at nuclear periphery

@pnas.org 2025
www.pnas.org/doi/10.1073/...