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Richards, Devenport et al. @princetonmolbio.bsky.social show that #melanocyte precursors form dynamic E-cadherin based attachments to surrounding #keratinocytes that stabilize migratory protrusions and sustain long-distance #migration as they colonize the #epidermis. rupress.org/jcb/article/...

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Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma - Nature Cell Biology Mohri et al. show that, in response to genotoxic stress, melanocyte stem cells undergo senescence-associated differentiation, causing their depletion and protecting them against melanomagenesis. This ...

☕Mohri et al. show that, in response to genotoxic stress, #melanocyte #StemCells undergo #senescence - associated differentiation, causing their depletion and protecting them against melanomagenesis. This process is suppressed by #carcinogens.
👉https://rdcu.be/eOAMp
bit.ly/4oNMu16

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… and we are very happy that our study on extrinsic control of melanocyte functions is published - kudos to @caroleluthold.bsky.social & co-authors! We found that distinct #ECM components impinge on #MITF, #melanocyte differentiation & #mechanosensation. Find out more here: doi.org/10.1038/s443...

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Sandra Iden @sandraiden.bsky.social @idenlab.bsky.social @uni-saarland.de @pharmascihub.bsky.social and co-workers show that #melanocyte #differentiation and #mechanosensation are differentially modulated by distinct extracellular matrix proteins. #ECM #MITF

www.embopress.org/doi/full/10....

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Transcriptional reprogramming triggered by neonatal UV radiation or Lkb1 loss prevents BRAFV600E-induced growth arrest in melanocytes - Oncogene Oncogene - Transcriptional reprogramming triggered by neonatal UV radiation or Lkb1 loss prevents BRAFV600E-induced growth arrest in melanocytes

Excited to share a paper I recently collaborated on, now published in Oncogene! 🧬 It was great working on this with an amazing team. Check it out here: www.nature.com/articles/s41...
#melanocyte #oncology #research #collaboration
@cnag-eu.bsky.social
@vhio.bsky.social

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