Two graphs display cumulative incidence percentages over time for Methadone and SROM treatments: A) Intention-to-treat analysis, B) Per-protocol analysis. Data points and 'No. at risk' tables are included.

Among adults with #OpioidUseDisorder, #SlowReleaseOralMorphine was associated with slightly higher treatment discontinuation and lower adherence vs #Methadone, but mortality risk was similar.

ja.ma/4sORJjF

Today's the day! Join us this afternoon ET:

#HarmReduction #HarmReductionSavesLives #Treatment #OverdoseEpidemic #EndOverdose #HarmReductionIsHealthCare #HarmReductionIsLove #PreventOverdose #PublicHealth #OverdosePrevention #BodilyAutonomy #Methadone #Buprenorphine #MOUD #DrugTreatment

Community pharmacies urged to plan ahead for Easter bank holidays with methadone safety resources The Community Pharmacy Patient Safety Group (CPPSG) has published resources to help community pharmacy teams manage patient safety risks when supplying methadone and other opioid treatment medicines…

The #CommunityPharmacyPatientSafetyGroup has published resources to help community pharmacy teams manage patient safety risks when supplying #methadone and other #opioid treatment medicines over the Easter bank holidays

#PharmacySafety #CPPSG

buff.ly/ZOxfAsr

Two graphs compare cumulative probability vs. ROI for pharmacy-based medication unit and pharmacist-dispensed methadone models. The first shows a 93.8% probability above a $15K ROI threshold, while the second shows 97.6% above the same threshold.

Pharmacy-based models for dispensing #Methadone for opioid use disorder produced positive return on investment, indicating financial viability for pharmacies and potential to increase access to treatment.

ja.ma/4bMtaha

#feasibility and Preliminary Efficacy of Empowered Relief in Patients With Chronic Pain Taking Methadone or Buprenorphine: Single-Arm National Pilot Study Background: Approximately 45% of individuals taking methadone or buprenorphine have chronic pain. These medications are commonly prescribed for chronic pain or opioid use disorder (OUD). To optimize pain management as well as reduce opioid-related symptoms (eg, craving) and risks (misuse and overdose), there is a critical need for a brief, effective, and accessible pain skills intervention for this population. Objective: This single-arm study aimed to examine the #feasibility and preliminary efficacy of online Empowered Relief (ER), a 1-session pain relief skills class, for individuals with chronic pain taking methadone or buprenorphine for chronic pain or OUD. Methods: A priori #feasibility criteria were defined as at least 75% of enrolled participants attending the ER class and the mean satisfaction rating of at least 8 on a 0‐10 scale. Participants were recruited nationally across the United States. Out of the 69 enrolled participants, 55 attended the ER class. Self-report measures were collected at baseline, immediately post class, and at follow-up points of 2 weeks and months 1‐3. Additionally, qualitative interviews were conducted in a small sample (n=14) to obtain in-depth participant feedback. Among the class attendees, 51 participants (27/51, 52.9% female; mean age 48.6, SD 12.2, range 28‐71 years) completed at least one follow-up survey, and treatment outcomes were analyzed using repeated measures ANOVA, with missing data imputed using linear regression. This analytic sample consisted of 24 participants taking methadone and 27 participants taking buprenorphine; 43.1% (22/51) endorsed at least≥2 OUD symptoms within the past 12 months, meeting the ( [Fifth Edition]) diagnostic criteria for current OUD. Results: #feasibility was achieved with 79.7% (55/74) attendance and mean 8.6 (SD 2) ratings of treatment appraisal and satisfaction. Qualitative feedback demonstrated high acceptability of the class content and delivery, with suggestions for refinements. Repeated-measures ANOVAs and FDR-corrected post hoc tests revealed significant reductions at 1 month post-ER class (primary endpoint) in pain intensity (Cohen =0.71), pain bothersomeness (Cohen =0.54), and pain interference (Cohen =0.61). At 3 months post-ER class, efficacy was maintained for pain intensity, pain bothersomeness, and pain interference (Cohen =0.28, 0.44, and 0.48, respectively). No significant time effects were observed for pain catastrophizing, sleep disturbance, physical function, fatigue, depression, anxiety, social isolation, and opioid craving. Conclusions: This study is the first to test ER in patients taking methadone or buprenorphine for pain or OUD. Findings showed #feasibility, acceptability, and preliminary evidence of treatment efficacy. Participant feedback will inform future study designs. These findings support a randomized trial to fully evaluate the efficacy and scalability of ER in this population. Trial Registration: ClinicalTrials.gov NCT05057988; https://clinicaltrials.gov/study/NCT05057988 International Registered Report Identifier (IRRID): RR2-10.2196/53784

JMIR Formative Res: #feasibility and Preliminary Efficacy of Empowered Relief in Patients With Chronic Pain Taking Methadone or Buprenorphine: Single-Arm National Pilot Study #ChronicPain #PainManagement #OpioidCrisis #EmpoweredRelief #Methadone

#PsychSciSky #DrugSky #PharmSky #MedSky #AddictionSci #NeuroSky #EpiSky #StatsSky #HealthPolicy @tandfresearch.bsky.social #methadone #buprenorphine #HarmReduction #HealthEquity #PublicHealth

Mark your calendar and join us for the free March Foundational Fridays session, focused on #Treatment medications!

#HarmReduction #HarmReductionSavesLives #OverdoseEpidemic #EndOverdose #PreventOverdose #PublicHealth #OverdosePrevention #BodilyAutonomy #Methadone #Buprenorphine

Over blue gradient, conversation bubbles in white and black with patterns at top right read, “FOUNDATIONAL FRIDAYS.” Below this, between black box outline, bold, all caps black copy reads, “THE BASICS OF MOUD". Some words are highlighted in yellow. Smaller black font at bottom middle reads, "March 27" and “12 p.m. — 2 p.m. ET”. Black and white NHRC 30th anniversary logo at bottom left.

🧵Each person knows their own needs best, & for some, that can include drug #Treatment &/or taking medications for #Opioid use disorder (MOUD). Learn more about these options & #MOUD including #Buprenorphine & #Methadone during our March Foundational Fridays...

bit.ly/FoundationalFridaysMOUD2026

Four graphs show driving and transit times to OTP facilities by urbanicity and race. Driving times are lower in urban areas. Transit times are much higher across all demographics. White people have the lowest transit times; other races are similar.

In Connecticut, median travel time to #Methadone treatment was 11 minutes by car and 42 minutes by public transit, with over half of census block groups lacking adequate transit access. ja.ma/4abewxR

Methadone: Public Transit is a Barrier for Accessing Treatment In a new study published in JAMA Network Open, Yale researchers examined the burdens for people who use public transit to access methadone treatment for opioid

New in @jamanetworkopen.com, @howellben.bsky.social et al highlight notable disparities in public transit access to #methadone treatment for OUD in Connecticut.
medicine.yale.edu/internal-med...

@gregggonsalves.bsky.social @emmabiegacki.bsky.social @yalesph.bsky.social @yaleschoolofmed.bsky.social

Exploring the effects of cannabidiol on pain sensitivity using quantitative sensory testing among individuals receiving methadone or buprenorphine for opioid use disorder: an open-label, proof-of-conc... While medications for opioid use disorder (MOUD) effectively treat opioid use disorder (OUD), concurrent pain management remains challenging. Cannabid…

Can #cannabidiol (CBD) help #pain in people with #OpioidUseDisorder? Our proof-concept study suggests CBD may modulate pain differently depending on whether people are on #methadone or #buprenorphine, with promising signals at lower doses and good tolerability.

shorturl.at/jlB7V

Over 1,170 patients are now receiving buprenorphine treatment, reflecting continued expansion of opioid substitution services and improved access for those seeking support.

https://bit.ly/4res8QJ

@drugsdotie @HRBdrugslibrary @MerchantsQuayIR #suboxone #methadone #dublin #health #drugs #hse

Over 1,170 patients are now receiving buprenorphine treatment, reflecting continued expansion of opioid substitution services and improved access for those seeking support.

https://bit.ly/4res8QJ

@drugsdotie @HRBdrugslibrary @MerchantsQuayIR #suboxone #methadone #dublin #health #drugs #hse

Over 1,170 patients are now receiving buprenorphine treatment, reflecting continued expansion of opioid substitution services and improved access for those seeking support.

https://bit.ly/4res8QJ

@drugsdotie @HRBdrugslibrary @MerchantsQuayIR #suboxone #methadone #dublin #health #drugs #hse

Over 1,170 patients are now receiving buprenorphine treatment, reflecting continued expansion of opioid substitution services and improved access for those seeking support.

https://bit.ly/4res8QJ

@drugsdotie @HRBdrugslibrary @MerchantsQuayIR #suboxone #methadone #dublin #health #drugs #hse

Join us for our semiannual #Methadone4Pain webinar series—this one taking place Nov 27 at 8pm ET. Don’t miss this opportunity to learn from an expert and connect with others prescribing #methadone for pain. buff.ly/ZkUulZ6 #hpm

#Tonsillectomy is associated with severe post-op pain. Cumulative 5-day opioid consumption and pain intensity was lower in patients given #methadone post-induction vs #fentanyl but at the expense of worse #PONV #bjaopen www.bjaopen.org/article/S2772-6096(25)00...

Over 1,170 patients are now receiving buprenorphine treatment, reflecting continued expansion of opioid substitution services and improved access for those seeking support.

https://bit.ly/4res8QJ

@drugsdotie @HRBdrugslibrary @MerchantsQuayIR #suboxone #methadone #dublin #health #drugs #hse

Trends in Methadone and Buprenorphine Use by Indication Among Medicaid Enrollees, 1999-2020. The graph plots prevalence of use per 1000 Medicaid enrollees, showing Methadone for pain, Methadone for OUD, and Buprenorphine for OUD.

#Methadone and #buprenorphine use for #OUD among Medicaid enrollees increased from 1999 to 2020, contrary to prior reports of declining methadone use in this population. ja.ma/47V6aL2

Join us for our semiannual #Methadone4Pain webinar series—this one taking place Nov 27 at 8pm ET. Don’t miss this opportunity to learn from an expert and connect with others prescribing #methadone for pain. buff.ly/ZkUulZ6 #hpm

Suboxone vs. Methadone: Which Works Best? Compare Suboxone and methadone for opioid use disorder. Learn how each works, pros and cons, and how to find the right fit in treatment.

Suboxone vs. Methadone: Which is better for OUD? Both save lives, but the right choice is personal. Methadone offers more structure; Suboxone offers more freedom.

#OUD #Methadone

Learn more👇

NEW ODPRN study found that nearly 60% of patients who began take-home methadone treatment during the first month of COVID-19 switched back to daily supervised dosing within 6 months.

Learn more at odprn.ca/research/pub...

@icesontario.bsky.social @unityhealthto.bsky.social

#methadone #OAT

Association Between Length of Buprenorphine or Methadone Use and Nonprescribed Opioid Use Among Individuals with Opioid Use Disorder: A Cohort Study - Xinyi Jiang, Gery P. Guy, Jill A. Dever, John S. ... Background: Opioid use disorder (OUD) affects millions of individuals each year in the United States. Patient retention in medications for opioid use disorder (...

Authors' Own Words: From Association Between Length of #Buprenorphine or #Methadone Use and Nonprescribed Opioid Use Among Individuals with #OpioidUseDisorder: A Cohort Study journals.sagepub.com/doi/abs/10.1...

Join us for our semiannual #Methadone4Pain webinar series—this one taking place Nov 27 at 8pm ET. Don’t miss this opportunity to learn from an expert and connect with others prescribing #methadone for pain. buff.ly/ZkUulZ6 #hpm

#HarmReduction #HarmReductionSavesLives #HarmReductionIsHealthCare #MOUD #Methadone #Buprenorphine #Opioids #Naloxone #CarryNaloxone #NaloxoneSavesLives #OverdoseEpidemic #SuicidePrevention #MentalHealthMatters #SupportNotStigma #EndTheStigma #OverdosePrevention #PreventOverdose #EndOverdose

New study co-authored by CP3’s Dr. Coleman Drake finds that a 2008 federal #methadone supply restriction led patients to switch to safer formulations, preventing an estimated 1,600 #overdose deaths over two years.

Read more: www.sciencedirect.com/science/arti...

Louise Vincent, 49, Drug User Who Led Harm Reduction Movement, Dies

In memoriam Louise Vincent, 49

(Link to archive copy in next post)

#nc #medsky #fentanyl #opioids #xylazine #naloxone #methadone

www.nytimes.com/2025/09/22/h...

PSA: #7-OH #withdrawal can be awful in a similar way to withdrawal from, e.g., #℞ #opioids /ates, misused #methadone, #poppy tea, #kratom (incl. extracts), or "pseudo" (mitragynine pseudoindoxyl). ALL MORas (analgesic–narcotic mu-opioid receptor agonists)—e.g. heroin, opium, kratom—can be addictive!

...but especially bad throughout my spine.

I've had three surgeries which have relieved much of the chronic neuropathy and positional pain but I grow older and we don't repair as well after a certain point.

#Bupenorphrine aka #Methadone is a wonderful, high efficacy and therefore low dose pain

NC turns to mobile clinics to expand substance use treatment State officials say mobile units will deliver methadone and other medications for opioid use disorder to rural and underserved areas.

NC state officials say mobile units will deliver #methadone and other medications for #opioid use disorder to #rural and underserved areas. #addictions #recovery @maiasz.bsky.social
www.northcarolinahealthnews.org/2025/09/16/n... via @NCHealthNews