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What if scientists accidentally created bacteria your body couldn’t recognize or fight? In this OWOH podcast, Jassi Pannu of @johnshopkinssph.bsky.social explains why research into #mirrorbacteria raises serious alarms.

🎧 Listen now to understand what’s at stake. onehealthtrust.org/news-media/p...

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The Legacy of Asilomar - JSTOR Daily The 1975 scientific conference laid the ground rules governing the next half century (and counting) of biological research and public scrutiny of it.

#BiologicalWeapons #GeneticEngineering #SyntheticBiology #GainOfFunction #MirrorBacteria
The Legacy of Asilomar
daily.jstor.org/the-legacy-o...

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That fear of creating a creature that can’t be controlled drove researchers to call for caution in mirror life research and a pointed ...

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Mirror Bacteria: A Threat to Ecosystem Balance? Mirror organisms could offer potential breakthroughs in medicine and technology, but they also raise significant questions regarding their impact on ecosystems.

Mirror bacteria are a fascinating yet deeply concerning concept emerging from synthetic biology. These organisms are designed to be built entirely from reversed biological molecules, opposite to the natural building blocks of life.
www.thephage.xyz/2025/01/04/m...

#SyntheticBiology #MirrorBacteria

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Our analysis suggests that #mirrorbacteria would likely #evade many immune mechanisms mediated by #chiral #molecules, #potentially causing #lethal #infection in humans, animals, and plants.

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„Voordat ik het rapport had gelezen dacht ik, misschien een beetje naïef, dat het wel los zou lopen. Maar gaandeweg begreep ik hun zorgen steeds beter.” Wilhelm Huck


Marcel aan de Brugh @nrcwetenschap.bsky.social #MirrorBacteria
www.nrc.nl/nieuws/2024/...

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#MirrorBacteria! 🪞🦠🧫😱

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Hi folks, here's your daily portion of technical reports on mirror bacteria! Enjoy! 📄
#mirrorbacteria

purl.stanford.edu/cv716pj4036

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Mirror Bacteria: Humanity's Next Frontier or Greatest Threat? Dive deep into the risks and future of "mirror bacteria," revolutionary synthetic organisms that defy natural biology. Uncover their potential to resh

Dive deep into the risks and future of "mirror bacteria," revolutionary synthetic organisms that defy natural biology. Uncover their potential to reshape ecosystems and human health.

#MirrorBacteria #Science #Biology #Ecosysten #Health #Biotech

Read.. www.freeastroscience.com/2024/12/mirr...

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#lifeOnEarth #mirrorlifemicrobe #mirrorbacteria

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‘Unprecedented risk’ to life on Earth: Scientists call for halt on ‘mirror life’ microbe research Experts warn that mirror bacteria, constructed from mirror images of molecules found in nature, could put humans, animals and plants at risk of lethal infections

Experts warn that mirror bacteria, constructed from mirror images of molecules found in nature, could put humans, animals and plants at risk of lethal infections.
The Guardian is a reliable source.
#mirrorbacteria

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*Hey, nice one with the more-or-less natural planet-eating Gray Goo scenario here #mirrorbacteria

amr.solutions/2024/12/12/mirror-bacter...

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Mirror mirror on the wall: Which paper should I read today? Adamala et al. 2024 #SyntheticBiology #Mirrorlife #MirrorBacteria #Biosecurity #mirrorSky🦠🪞🦠

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Figure 1.1: Chiral molecules have non-superimposable mirror images
A. The amino acid glycine is an achiral molecule, as it can be superimposed on its mirror image. B. All other canonical amino acids are chiral molecules, with two non-superimposable mirror images. Alanine is illustrated as an example. Even if D-alanine is rotated 180° so its amino and carboxyl groups are in the same orientation as L-alanine, as shown in the figure, the two cannot be superimposed because the methyl group in L-alanine is projecting into the page but the methyl group in d-alanine is projecting out of the page.

Figure 1.1: Chiral molecules have non-superimposable mirror images A. The amino acid glycine is an achiral molecule, as it can be superimposed on its mirror image. B. All other canonical amino acids are chiral molecules, with two non-superimposable mirror images. Alanine is illustrated as an example. Even if D-alanine is rotated 180° so its amino and carboxyl groups are in the same orientation as L-alanine, as shown in the figure, the two cannot be superimposed because the methyl group in L-alanine is projecting into the page but the methyl group in d-alanine is projecting out of the page.

Figure 1.3: Mirror-image amino acids compose mirror-image peptides that fold into mirror-image proteins All natural amino acids except glycine are chiral, and only the L-enantiomers are used in natural protein Substituting the L-amino acids for their mirror image D-amino acid enantiomers would result in a mirror-imag polypeptide chain. The interactions between the side chains for amino acids in the D-peptide are the same as th L-peptide, but with the opposite orientation. Thus, the mirror-image peptide chain folds into a protein that is th mirror image of its natural chirality counterpart. (Structure image for example protein, carbonic anhydrase, produce by Pymol 3.0.0 from Protein Data Bank accession number 1CA2.)

Figure 1.3: Mirror-image amino acids compose mirror-image peptides that fold into mirror-image proteins All natural amino acids except glycine are chiral, and only the L-enantiomers are used in natural protein Substituting the L-amino acids for their mirror image D-amino acid enantiomers would result in a mirror-imag polypeptide chain. The interactions between the side chains for amino acids in the D-peptide are the same as th L-peptide, but with the opposite orientation. Thus, the mirror-image peptide chain folds into a protein that is th mirror image of its natural chirality counterpart. (Structure image for example protein, carbonic anhydrase, produce by Pymol 3.0.0 from Protein Data Bank accession number 1CA2.)

#MedSky🧪 #IDsky #MicroSky #Syntheticbiology #publichealth This report describes the technical feasibility of creating #mirrorbacteria and the potentially serious and wide-ranging risks that they could pose to humans, other animals, plants, and the environment.
stacks.stanford.edu/file/druid:c...

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