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New issue online! ➡️ link.springer.com/journal/4432...

The cover highlights the article by S Hirschberger, S Kreth, M Hübner & al 👉 #MitochondrialDamage drives #Tcell immunometabolic paralysis after major surgery: link.springer.com/article/10.1...

Scientific illustration by M Hübner; S Hirschberger

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#MitochondrialDamage drives #Tcell immunometabolic paralysis after major surgery

By S. Hirschberger, S. Kreth, M. Hübner and colleagues at Ludwig-Maximilian-University

🗞️ doi.org/10.1038/s443...

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Quelle: Chemical Proteomics Reveals Human Off‑Targets of Fluoroquinolone-Induced Mitochondrial Toxicity, 2024
#FQtoxicityAwarenessDay
#FQAD #Mitochondria #Fluoroquinolones #MitochondrialDamage #Antibiotics 2/2

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MYBPC3-deleted hiPSC-CMs showed characteristics of #HeartFailure, abnormal calcium handling, increased ROS levels, #MitochondrialDamage, and aberrant activation of the PI3K/AKT/FOXO3a pathway, which was reversed upon #melatonin addition. #medsky
#OpenAccess:

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My connective tissue is completely wrecked, same with my cells. #Mitochondrialdamage #ConnectiveTissueDisorder. I have to pay for all treatment attempts myself. (4/6)

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