Researchers show that VPS13D regulates #EpilepticSeizures by modulating #MitochondrialFission and #Autophagy, suggesting therapeutic targeting of VPS13D-mediated mitochondrial dynamics as a novel strategy for #Epilepsy.

#OpenAccess: doi.org/10.1016/j.ge...

#Pericyte #Retinopathy

Pericytic & endothelial Epac1⏫in🐭#IschemicRetinopathy #DiabeticRetinopathy

Epac1 KO🐭resistant to IR loss of pericyte & capillary

Epac1 in👤retinal pericytes->
#MitochondrialFission
Apoptosis

H Liu, X Cheng labs #IOVS 2023
iovs.arvojournals.org/article.aspx...