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High-Throughput Tear Proteomics Reveals Multi-Faceted Signatures of Thyroid Eye Disease | IOVS | ARVO Journals

High-Throughput Tear Proteomics Reveals Multi-Faceted Signatures of Thyroid Eye Disease #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Thrilled to see the revised version of the “Optics & Visual Diet in Myopia” paper commissioned by @nationalacademies.org for Focus on #Myopia consensus report now published in #IOVS @arvoinfo.bsky.social iovs.arvojournals.org/article.aspx... #NationalEyeInstitute #Optics #Vision @cvsuor.bsky.social

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Alteration of Tear Metabolomics Profiling in Infants With Retinopathy of Prematurity | IOVS | ARVO Journals

Alteration of Tear Metabolomics Profiling in Infants With Retinopathy of Prematurity #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Metabolomic Profiling of Aqueous Humor From Glaucoma Patients Identifies Metabolites With Anti-Inflammatory and Neuroprotective Potential in Mice | IOVS | ARVO Journals

Metabolomic Profiling of Aqueous Humor From Glaucoma Patients Identifies Metabolites With Anti-Inflammatory and Neuroprotective Potential in Mice #IOVS iovs.arvojournals.org/article.aspx...

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Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker | IOVS | ARVO Journals

Comprehensive Proteomic Profiling of Exfoliation Glaucoma Via Mass Spectrometry Reveals SVEP1 as a Potential Biomarker #IOVS iovs.arvojournals.org/article.aspx...

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The Signature of Serum Modified Nucleosides in Uveitis | IOVS | ARVO Journals

The Signature of Serum Modified Nucleosides in Uveitis #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment | IOVS | ARVO Journals

Metabolomic Characteristics of Aqueous Humor in Wet Age-Related Macular Degeneration and the Impact of Anti-VEGF Treatment #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy | IOVS | ARVO Journals

Elevated Very-Long-Chain Ceramides in the Vitreous Humor of Patients With Proliferative Diabetic Retinopathy #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery | IOVS | ARVO Journals

Aqueous Proteomic and Metabolomic Profiles in Low-Energy vs High-Energy Femtosecond Laser-Assisted Cataract Surgery #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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Metabolic Characteristics of Sclera in Lens-Induced Myopic Guinea Pigs | IOVS | ARVO Journals

Metabolic Characteristics of Sclera in Lens-Induced Myopic Guinea Pigs #IOVS #MassSpec iovs.arvojournals.org/article.aspx...

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#Pericyte-to-Pericyte #TunnelingNanoTube in normal human Macula👁️
289 TNT 11 donors

All b/w retinal capillaries (none with arteriole/venule)
Closely intertwined with GFAP+ astrocyte processes😈
Density superficial > intermediate ~ deep capillary plexi

#IOVS 2024
iovs.arvojournals.org/article.aspx...

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#TGFβ1 on #Hyaluronan turnover + HA metabolic regulators in cultured orbital fibroblast👁️

Most HA are pericellular, not shed into medium
⏫HAS1 not HAS2/3 (HA synthase)
⏬HYAL1 not HYAL2
⏬CEMIP
⏫TMEM2
Shifted to high mol weight HA species production

#IOVS 2024
iovs.arvojournals.org/article.aspx...

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#Pericyte #Retinopathy

Pericytic & endothelial Epac1⏫in🐭#IschemicRetinopathy #DiabeticRetinopathy

Epac1 KO🐭resistant to IR loss of pericyte & capillary

Epac1 in👤retinal pericytes->
#MitochondrialFission
Apoptosis

H Liu, X Cheng labs #IOVS 2023
iovs.arvojournals.org/article.aspx...

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Reading pixelized paragraphs of Chinese characters using simulated prosthetic vision http://tinyurl.com/68xwosv #IOVS

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