A targeted metabolomic method to detect epigenetically relevant metabolites To develop a sensitive, versatile analytical method capable of simultaneously detecting epigenetically relevant metabolites without chemical derivatiz…

A targeted metabolomic method to detect epigenetically relevant metabolites #MolMetab #MassSpec www.sciencedirect.com/science/arti...

Whole-body p21 transgenic🐭
#SkeletalMuscle atrophy fibrosis
⏬Treadmill Grip strength
SkM transcriptomic #Senescence #SASP
⏬OXPHOS
⏫myonuclei & interstitial cell #DNADamage

p21 OE does Not increase p16 in SkM

Nathan LeBrasseur lab #MolMetab 2023
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The diet-derived gut microbial metabolite 3-phenylpropionic acid reverses insulin resistance and obesity-associated metabolic dysfunction #MolMetab #MassSpec www.sciencedirect.com/science/arti...

Postpartum Brain Changes Influence Temperature Preferences | Geekoo New research links postpartum females' preference for cooler environments to neurobiological changes in the brain’s thermoregulation center.

Research reveals that #postpartum females prefer cooler environments, a behavior linked to specific neuronal changes in the #brain’s preoptic area. C. Wang et al #MolMetab @bcmhouston.bsky.social @geekoonews.bsky.social geekoo.news/postpartum-b...

Postpartum Moms Prefer Cooler Temps, Brain Changes Explain Why - Neuroscience News Pregnancy and lactation trigger major physiological changes, including shifts in body temperature and environmental preferences.

Check out new #research on what causes #postpartum mothers to prefer cooler temperatures. #CWang et al #MolMetab @bcmhouston.bsky.social @neurosciencenews.bsky.social neurosciencenews.com/postpartum-b...

Scientists reveal surprising way pregnancy changes your brain Researchers conducted a study using mice models to understand how pregnancy affects temperature regulation.

New research has discovered an unexpected way #pregnancy alters a mother's temperature preferences—by changing the #brain. C. Wang explains her findings in animal research models. @bcmhouston.bsky.social #MolMetab www.newsweek.com/pregnancy-br...

Mustn1, a matricellular microprotein deposited by #SkeletalMuscle & intramuscular arteriolar #SmoothMuscleCell (& pericyte/EC/FAP as well?) (contributing 7~35% Mustn1)

Global Mustn1 KO🐭➡️
10%⏫ collagen in♀️(not♂️) SkM at 14 d injury by cardiotoxin

#MolMetab 2024
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