30 NEURONS, STRUCTURE AND FUNCTION OF THE NERVOUS MESSENGERS #50LAM_ANATOMY_ENG
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#neurons #nervoussystem #neuronstructure #axon #dendrites #myelinsheath #synapse #neurotransmitters #sensoryneurons #motorneurons
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
Representative images of the ALS sod-1 A4VM model show motor neuron degeneration in animals fed Escherichia coli followed by oxidative stress induced by 5 mM paraquat. Cholinergic motor neurons were visualized with unc-17p::GFP. After 24 hours of exposure, representative images of sod-1 A4VM animals were captured, showing those without (top) and with (bottom) neurodegeneration. Enlarged images in the right panels highlight motor neuron defects, indicated by red circles.
#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw
Representative images of the ALS sod-1 A4VM model show motor neuron degeneration in animals fed Escherichia coli followed by oxidative stress induced by 5 mM paraquat. Cholinergic motor neurons were visualized with unc-17p::GFP. After 24 hours of exposure, representative images of sod-1 A4VM animals were captured, showing those without (top) and with (bottom) neurodegeneration. Enlarged images in the right panels highlight motor neuron defects, indicated by red circles.
#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw
Representative images of the ALS sod-1 A4VM model show motor neuron degeneration in animals fed Escherichia coli followed by oxidative stress induced by 5 mM paraquat. Cholinergic motor neurons were visualized with unc-17p::GFP. After 24 hours of exposure, representative images of sod-1 A4VM animals were captured, showing those without (top) and with (bottom) neurodegeneration. Enlarged images in the right panels highlight motor neuron defects, indicated by red circles.
#Probiotics can influence neuronal health, but how does this happen? @aaballay.bsky.social &co show that #Enterococcus faecium activates an intestinal NHR-86/CYP450 pathway that lowers #ROS and protects #MotorNeurons, in a nematode model of #ALS @plosbiology.org 🧪 plos.io/3Mc0iVw
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
#Amyotrophiclateralsclerosis (#ALS) can be caused by repeat expansions in C9orf72. A new study by David Vilchez et al. shows G3BP1 exhibits enhanced interaction with Nup107 in #motorneurons derived from patient iPSCs with C9orf72 mutations. @thevilchezlab.bsky.social
➡️https://tinyurl.com/zm2ujupc
Left: Image of the Drosophila melanogaster third instar larval ventral nerve cord used to examine mitochondrial morphology. Green fluorescence labels neuronal mitochondrial clusters decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Bruchpilot protein, a component of active zones. Image credit: Bhagaban Mallik. Right: Image of synaptic boutons at the Drosophila melanogaster third instar larval neuromuscular junction rendered into three dimensions to quantify volumes of synaptic mitochondria. Green fluorescence labels neuronal mitochondria localized to the presynaptic boutons. Mitochondria are decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Discs Large protein, an organizer of the postsynaptic density in the muscle. Image credit: Bhagaban Mallik and Thomas Moninger.
How do different tissues respond to mitochondrial dysfunction? @candrewfrank.bsky.social &co show that Complex I depletion triggers ROS-driven compensatory signaling in #MotorNeurons, but degeneration in muscles, with implications for #MitochondrialDisease @plosbiology.org 🧪 plos.io/4nLUIGJ
Left: Image of the Drosophila melanogaster third instar larval ventral nerve cord used to examine mitochondrial morphology. Green fluorescence labels neuronal mitochondrial clusters decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Bruchpilot protein, a component of active zones. Image credit: Bhagaban Mallik. Right: Image of synaptic boutons at the Drosophila melanogaster third instar larval neuromuscular junction rendered into three dimensions to quantify volumes of synaptic mitochondria. Green fluorescence labels neuronal mitochondria localized to the presynaptic boutons. Mitochondria are decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Discs Large protein, an organizer of the postsynaptic density in the muscle. Image credit: Bhagaban Mallik and Thomas Moninger.
How do different tissues respond to mitochondrial dysfunction? @candrewfrank.bsky.social &co show that Complex I depletion triggers ROS-driven compensatory signaling in #MotorNeurons, but degeneration in muscles, with implications for #MitochondrialDisease @plosbiology.org 🧪 plos.io/4nLUIGJ
Left: Image of the Drosophila melanogaster third instar larval ventral nerve cord used to examine mitochondrial morphology. Green fluorescence labels neuronal mitochondrial clusters decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Bruchpilot protein, a component of active zones. Image credit: Bhagaban Mallik. Right: Image of synaptic boutons at the Drosophila melanogaster third instar larval neuromuscular junction rendered into three dimensions to quantify volumes of synaptic mitochondria. Green fluorescence labels neuronal mitochondria localized to the presynaptic boutons. Mitochondria are decorated by a transgenically expressed Mito-GFP protein. Magenta fluorescence labels the Drosophila Discs Large protein, an organizer of the postsynaptic density in the muscle. Image credit: Bhagaban Mallik and Thomas Moninger.
How do different tissues respond to mitochondrial dysfunction? @candrewfrank.bsky.social &co show that Complex I depletion triggers ROS-driven compensatory signaling in #MotorNeurons, but degeneration in muscles, with implications for #MitochondrialDisease @plosbiology.org 🧪 plos.io/4nLUIGJ
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" carboncopies.org/Events/Journ... #Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience
Join Us for the Memory Decoding Journal Club! "Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons" carboncopies.org/Events/Journ...
#Neuroscience #MemoryResearch #MotorNeurons #JournalClub #BrainScience #Carboncopies #AspirationalNeuroscience
🚀 New paper out now! We propose a three-determinant anatomical classification of ALS motor phenotypes — based on onset region, symptom spread, and UMN/LMN involvement. 🧠💥
🔗 neurolrespract.biomedcentral.com/articles/10....
#ALS #Neurology #ALSresearch #MotorNeurons #PrecisionMedicine
How Your Muscles Really Work 🧠💪
#muscles #neuroscience #movement #physiology #motorneurons #bicep #nervoussystem #GABA #acetylcholine #flexors #extensors
A minimally invasive, drug-free intervention using #ElectricalStimulation on sensory #SpinalNerves can reactivate #MotorNeurons and enhance leg #MuscleStrength and #walking in adults with #SpinalMuscularAtrophy.
#Neurodegeneration #EpiduralElectricalStimulation
Movement is magic. ➡️ 🦋 #motorneurons #ALS #biotech #scienceskies #sciencesky #neuro #neurodegeneration