evidenced by elevated levels of inflammatory proteins like #ferritin, D-dimer & specific #cytokines (IL-6). In severe cases, there is also evidence of #myeloidcell inflammation & overactivation of the complement system.

Single-cell transcriptional landscape of peripheral myeloid cells in autoimmune diseases Immunology; Components of the immune system; Transcriptomics

www.cell.com/iscience/ful...

#autoimmune #singlecell #myeloidcell

#LaiGuanNg joining the #HunterMeetingOz from #Shanghai #JiaoTongUniversity a leader in #MyeloidCell biology.

Beyond T cell exhaustion: TIM-3 regulation of myeloid cells We provide a comprehensive review of 20 years of research on TIM-3 functions in myeloid cells and T cell exhaustion.

@dixon-lab.bsky.social, Gonzalo Fernandez Lahore, & @kuchroolab.bsky.social discuss the emerging roles for #TIM3 in regulating #MyeloidCell #immune responses!

#MyeloidCell path to #Malignancy: insights into #Liver #Cancer

SUPERLATIVE OPEN ACCESS REVIEW from Christel Ramirez & @leilaakkari.bsky.social at @cp-trendscancer.bsky.social 👏

www.cell.com/action/showP...

Myeloid activation clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer Murphy and Miyamoto et al. have developed a non-T cell targeting immune therapy for metastatic ovarian cancer. This approach induces tumor regression by ac

A great way to start my BlueSky journey! Very excited to share the first research article from my lab! #MyeloidCell #OvarianCancer #IL27 #Omentum #Ascites @jexpmed.bsky.social

The acid-sensing receptor GPR65 on tumor macrophages drives tumor growth in obesity Tumor acidity and signaling through GPR65 on tumor macrophages drive accelerated growth of obesity-associated cancers.

Continuing my posts on recent #myeloidcell papers in #ScienceImmunology, Sreya Bagchi, Edgar G. Engleman, & al. reported that tumor-associated macrophages accumulate and drive tumor growth in obesity-associated cancers due to enhanced signaling through the acid-sensing receptor GPR65.