Reciprocal regulation of fibroblast–macrophage equilibrium governs skin integrity Nature Immunology - Turley, Buechler and colleagues show that dermatopontin-expressing fibroblasts provide CSF1 to form a supportive niche for skin-resident macrophages. This interaction is...

So glad to share our new work in #NatureImmunology highlighting that #fibroblast-#macrophage dialogue is a cornerstone of skin integrity in health and disease. Big congrats to all the authors at #UofT and #Genentech for their tireless efforts. Looking for #PDs to continue this work~ rdcu.be/e50PJ

El truco del cáncer para volverse invisible al sistema inmune Un estudio identifica cómo la secretogranina 2 apaga defensas al activar LILRB4, clave en el camuflaje de tumores y la inmunoterapia moderna. Hay tumores que no ganan por fuerza bruta, sino por sigilo...

El truco del cáncer para volverse invisible al sistema inmune #Cancer #Inmunoterapia #Oncologia #Ciencia #Salud #Investigacion #SistemaInmune #NatureImmunology #UTSouthwestern #Tumores #Biomedicina #23deenero #felizviernes donporque.com/el-truco-del...

A unified multimodal single-cell framework reveals a discrete state model of hematopoiesis in mice - Nature Immunology Grimes and colleagues integrate multiomic features to create a framework that allows the isolation of discrete cell states across hematopoiesis and exploit the underlying gene regulatory networks to i...

Congrats to Lee Grimes, Nathan Salomonis and colleagues @cincychildrens.bsky.social for their latest publication in #NatureImmunology shedding new light on how #BoneMarrow produces blood cells. www.nature.com/articles/s41...

Slaying the pre-TCR beast - Nature Reviews Cancer In a study published in Nature Immunology, Fuentes et al. demonstrate that the pre-T cell receptor (TCR) is expressed in leukaemia-initiating cells in patients with T cell acute lymphoblastic leukaemia, and that targeting it can inhibit tumour progression.

In a study published in #NatureImmunology, Fuentes et al. demonstrate that the pre-T cell receptor (TCR) is expressed in leukaemia-initiating cells in patients with T cell acute lymphoblastic leukaemia, and that targeting it can inhibit tumour progression.

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Latest news from #CancerResearch: CIBSS member Bertram Bengsch and colleagues uncover how IL-21 signalling pathway plays a decisive role in the efficacy of combined #ImmunoTherapies against #SkinCancer. Findings were recently published in #NatureImmunology
www.cibss.uni-freiburg.de/news/immunot...

Neue Erkenntnisse für Hautkrebs-Therapie: Forschende des CCCF der #UniklinikFreiburg finden die Erklärung, warum eine Kombinationstherapie gegen schwarzen #Hautkrebs besser wirkt als Einzelwirkstoffe. Die #Studie wurde in #NatureImmunology veröffentlicht. Mehr: t1p.de/hocfn
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