the American Geriatrics Society warns against the use of #nitrofurantoin in patients older than 65 years with creatinine clearance of less than
30 mL/min or for prolonged courses.

median age 60-70 yrs, mostly women, 1 in 5000 exposures, 80% acute reaction, 20% chronic presentation #nitrofurantoin pulmonary reaction

Pulmonary toxicity due to #nitrofurantoin has 2 main presentations: (1) an acute onset hrs-wks after a short course & (2) a chronic onset developing after 1-6mo of tx

Nitrofurantoin-induced lung disease and prophylaxis of urinary tract infections - Primary Care Respiratory Journal Primary Care Respiratory Journal - Nitrofurantoin-induced lung disease and prophylaxis of urinary tract infections

#nitrofurantoin induced pulmonary reaction pic Ref www.nature.com/articles/pcr...

#Pharmacology18
#Antibiotics #NucleicAcidSynthesisInhibitors #NursingStudents #MedicalEducation #MedSchool #NursingSchool #PharmaNotes #InfectiousDiseases #Sulfonamides #Fluoroquinolones #Metronidazole #Nitrofurantoin #AntimicrobialTherapy #MedStudy #PharmaFacts #Microbiology #HealthcareEducation

exposures, 80% acute reaction, 20% chronic presentation #nitrofurantoin pulmonary reaction

Pulmonary toxicity due to #nitrofurantoin has 2 main presentations: (1) an acute onset hrs-wks after a short course & (2) a chronic onset developing after 1-6mo of tx

#nitrofurantoin induced pulmonary reaction

⭐️ Target product profiles to #develop #paediatric #azithromycin & #nitrofurantoin to #treat #bacterial #infections in #children ⭐️
www.who.int/publications...

⭐️ Call for #medicine #manufacturers to apply for #WHO #Prequalification ⭐️
extranet.who.int/prequal/site...

#BetterMeds4Kids @who.int #GAP-f