⏪ G&D RECAP ⏪

🗓️ May 2025
RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.full

#DNArepair #BRCA1 #nucleases #PARP #cancer

🌟G&D SPOTLIGHT 🌟

RESEARCH PAPER: MRN–CtIP, EXO1, and DNA2–WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage
By Seppa et al., and Alessandro Vindigni
➡️ https://genesdev.cshlp.org/content/39/9-10/582.abstract

#DNArepair #BRCA1 #nucleases #PARP #cancer

This review summarizes the development of #DNA #Nucleases and delivery vectors, highlighting the progress and future potentials of in vivo #GeneTherapy for #GeneticDisorders, #DegenerativeDiseases, and #Cancers. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...

CRISPR technology: A decade of genome editing is only the beginning A review discusses the current state of CRISPR-mediated genetic manipulation in human cells, animals, and plants and considers its future potential.

#Medsky🧪 #immunosky #Academicsky overview the origins & utility of #CRISPR-based #genomeediting,
www.science.org/doi/10.1126/...
And What’s the Difference Between #Cas9 and #Cas12a #Nucleases?
www.the-scientist.com/what-s-the-d...