And the full rounds are available here
www.youtube.com/watch?v=_iXs...
Excellent, thorough overview of all sorts of strange and wonderful nephrotoxicity one can expect to see
@aisha-shaikh.bsky.social #NephGR #OncoNeph
Figure 1 Timing of recurrence of various plasma cell dyscrasia in kidney transplant allograft. LCCN: light chain cast nephropathy, LCPT: light chain proximal tubulopathy, C3G: C3 glomerulopathy, PGNMID: proliferative glomerulitis with immunoglobulin deposits
Figure 2 Decision Tree for MM Patients with ESKD Based on Risk Category and Response to Therapy
Plasma cell dyscrasia and transplant - excellent review in @kidneyint.bsky.social
www.kidney-international.org/article/S008...
From @nymurakami.bsky.social et al
#NephSky #OncoNeph
Check out this from Dr Meghan Sise #NephGR for us on the topic
youtu.be/qFYVhjpnYIU?...
#OncoNeph #NephSky
Dr Meghan Sise presenting on serum cr/cystatin outcomes in patients treated with cisplatin or carboplatin
#Onconeph #ERA25
Continuing our discussion on oncological emergencies from last week, let's tackle malignant hypercalcemia, which occurs in 20-30% of malignancies with a grim prognosis.
A must-know🧵 for medicine trainees!
#PhysiologyFriday #MedSky #NephSky #OncSky #Onconeph #MedStudentSky
Take home messages for ICI nephrotoxicity
Take home messages for ICI nephrotoxicity
Dr Rosner had cool ‘key messages’ interspersed throughout his talk
#ISNWCN #Nephsky #Onconeph
Figure 4 Approach to immune checkpoint inhibitor (ICPI) nephrotoxicity.∗Treat the underlying disease. AKI, acute kidney injury; ATI, acute tubular injury; ATIN, acute tubulointerstitial nephritis; GN, glomerulonephritis; IrAE, immune-related adverse event; RBC, red blood cell; RTEC, renal tubular epithelial cell; WBC, white blood cell.
This is the algorithm he prefers from a 2020 for biopsy and management www.kidney-international.org/article/S008...
2020 @kidneyint.bsky.social - looks #OpenAccess
#ISNWCN #NephSky #Onconeph
Watch this space for biomarkers I say 😎
Electrolyte issues with CAR-T
Conclusions AKI mostly CRS Don’t forget HypoPO4
And don’t forget electrolyte issues from CAR-T
HypoNa likely from Cancer
Hypo from po intake
HypoPO4 truly from CAR-T
#ISNWCN #NephSky #Onconeph
Management of AKI in CAR-T induced CRS
Yale pharmacy guidance for management
Management is mostly around supportive care
Steroids
IL-6 inhibition in more severe cases
#onconeph #NephSky #ISNWCN
