#Osteopetrosis

I miss running . Having a disability that impedes you from doing what you loved really sucks . Can’t skate ( risk of f***ing up my hips more), can’t run ( high impact sports will raise risk) , and over all even in walking I’m always reminded that this will only get worse . 💔 #Osteopetrosis

Images in Rheumatology

Not Everything is Osteoporosis: Multiple Low-Impact Fractures in an Adult Female Patient

📖 doi.org/10.3899/jrhe...

#pycnodysostosis #osteopetrosis

Adoptive Transfer of Lepr+ Bone Marrow Cells Attenuates the Osteopetrotic Phenotype of db/db Mice How does the hormone leptin help bones grow and develop properly? Understanding exactly how leptin works in bones could help develop treatments for bone diseases and growth disorders in humans.

Researchers found that bone marrow transplantation containing leptin-responsive cells can successfully treat #osteopetrosis and other bone development disorders.

#AcademicSky #nutrition #bonehealth

DOI: 10.3390/ijms26115120

Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2, say Jing Ze Wu, Sergio Grinstein, Spencer Freeman and colleagues @sickkidsto.bsky.social: rupress.org/jcb/article/...

#Immunology #Membrane #lipid #lysosomes #osteopetrosis

Wu et al @sickkidsto.bsky.social show that Snx10 regulates PI(3,5)P2 accumulation on #lysosomes by controlling PI(3)P delivery. Deleting Snx10 inhibits ClC-7, thereby impairing (phago)lysosome resolution. This mechanism may account for Snx10-related #osteopetrosis. rupress.org/jcb/article/...

Definition of osteopetrosis Explore the definition of the word "osteopetrosis" with example sentences, synonyms, and related terms to improve your English skills.

osteopetrosis
- An inherited disorder characterized by an increase in bone density; in severe forms the bone marrow cavity may be obliterated

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#definition #osteopetrosis #meaning #english #ielts