Time for an update? Research #exome #sequencing can achieve up to 95% sensitivity in detecting #PKD1 variants, rivaling traditional methods. bit.ly/4cVfb9T #AKPKD #Pseudogenes

⭐NAR Breakthrough ⭐
New study identifies a 6-nt miR-17 site in the #PKD1 3′UTR that limits PKD1 expression. Targeting this site boosts PKD1 protein and reduces cyst burden in #ADPKD models—highlighting a promising oligo-based strategy @vishal-d-patel.bsky.social
🧬Read more: doi.org/10.1093/nar/...

Variant Location in PKD1 Nontruncating Mutations Linked to ADPKD Progression | Docwire News Study findings suggest that the location of nontruncating PKD1 gene variants could serve as a marker of progression of autosomal dominant polycystic kidney disease (ADPKD).

Study findings suggest that the location of nontruncating #PKD1 variants could serve as a marker of progression of #ADPKD. #kidneydisease #nephrology #nephsky docwirenews.com/post/variant...