An image of a single lipid nanoparticles, in 2 SMLM channels for surface reagent and targeting ligand and a diffraction-limited image of RNA cargo.

It's #FluoresenceFriday and today we have a a single #LipidNanoParticle ( #LNP ), taken with our #LNPProfiler and #AutoLNP using the #Nanoimager: 2 #SMLM channels #PanLNP in magenta and #ligand in yellow, and diffraction-limited #RNA cargo in cyan.
Read our blog post on LNP ligand: t.co/B5L80p6TfR

LNPs imaged with the Nanoimager, with and without RNA cargo and ligand.

Did you know that #LNPProfiler uses self-blinking dyes for #dSTORM #imaging of #LipidNanoParticles? No need for imaging buffer, our #PanLNP and ligand reagent are self-blinking and ready for #SuperResolution with a single staining step!

Read more hubs.li/Q03jfNfb0 Join our webinar hubs.li/Q03jfQmV0

Application Kit: LNP Profiler next to a computer screen showing AutoLNP and next to the Aplo Scope.

Unlock the future of #LipidNanoParticles ( #LNP) #research with #LNPProfiler and #AutoLNP! Each kit includes Assay Chips, SMLM-compatible dyes for #PanLNP and ligands, and a sequence-independent #RNA dye. Find us at the LNP Formulation and Process Development Summit to!
#SMLM #SuperResolution

In the montage here we have a #SuperResolution #SMLM image of #PanLNP in magenta and #ligand in yellow, and a diffraction-limited image of #NucleicAcids in cyan. When overlayed together, scientists can immediately see what fraction of their LNPs actually carry both RNA cargo and targeting ligand.