Did you miss yesterday’s Microscopy Masters #webinar?
It was great! @Richard Lincoln, PhD, shared his research in the Hell lab
You can now watch the webinar recording on our website:
zurl.co/92vjr
#PALMimaging #Nanoimager
Curious what your #ExtracellularVesicles look like at 20 nm resolution? Ever wondered about their biomarker distribution? 🤔
Apply now to win a FREE 3-month #Nanoimager subscription in ONI’s annual EV Competition! 🔬
🥇 Apply here: hubs.ly/Q03vd1bm0
👋 ELMI starts tomorrow — will we see you there?
Join ONI at #ELMI2025 in Heidelberg for hands-on workshops, super-res imaging, and the latest in single-molecule discovery.
🧪 See you at EMBL June 3–6!
#EMBL #Nanoimager #AploScope #Microscopy #SuperResolution #dSTORM #LightMicroscopy #ONI
🚨 Upcoming Training 🚨
Live from the Lab: EV Imaging Training
🗓️ Thursday, June 26
🕚 11:00 EST | 18:00 CET
*Enrollment requires purchase of the EV Profiler 2 kit.
Register now - hubs.li/Q03pfp7X0.
#extracellularvesicles #Nanoimager #SuperResolution #Microscopy #ONI #dSTORM #SingleMoleculeImaging
#CanSEV, the Canadian Society for #ExtraCellularVesicles starts today! Find us at the The Neuro, Montreal, and check out our latest offers in EV research!
#CanSEV2025, #EVProfiler2 #AutoEV #Nanoimager #AploScope #dSTORM #SMLM #SuperResolution #ExtraCellularVesicles
Svea Wilken's poster Barcoding Through Hybridisation Kinetics: Deciphering Single-Molecule Identities.
Mirjam Kummerlin's poster DNA Lightbulbs: Tunable Fluorogenic DNA Probes Advances Single-Molecule Imaging.
Poster Session and Drinks
Pip Timmins's talk in the meeing.
Great time at the #SMBio2025 in Oxford with so many great #SingleMolecule works! #DNA - #protein interactions to #virology and #microbiology, it was truly inspiring. We were particularly pleased to see our #Nanoimager on a couple of posters 💪.
What a privilege to support a meeting like that!
Missed our webinar? Watch it here pages.oni.bio/webinar-lnp-....
#LNP #LipidNanoparticles #DrugDiscovery #DrugDevelopment #ResearchAndDevelopment #LifeScience #Nanoimager #LNPProfiler #AutoLNP #SuperResolution #Microscopy #Microscope #SMLM #Innovation #Biotech #Biotechnology #ProductLaunch
An image of a single lipid nanoparticles, in 2 SMLM channels for surface reagent and targeting ligand and a diffraction-limited image of RNA cargo.
It's #FluoresenceFriday and today we have a a single #LipidNanoParticle ( #LNP ), taken with our #LNPProfiler and #AutoLNP using the #Nanoimager: 2 #SMLM channels #PanLNP in magenta and #ligand in yellow, and diffraction-limited #RNA cargo in cyan.
Read our blog post on LNP ligand: t.co/B5L80p6TfR
Pip Timmins and Shaked Ashkenazi at the SMBio 2025 in the University of Oxford.
Our Pip Timmins and Shaked Ashkenazi are in #SMBio2025 in the University of Oxford! Find us to chat about the #SingleMolecule capabilities of our #Nanoimager and #AploScope. We are looking forward to the exciting talks and posters in the next couple of days!
🔬Did you know that we offer workshops at #ELMI2025? Don't miss our experts ( #ELMI ):
Check out @embl.org website for more details on how to register t.co/3uaJg2gDv4
#SMLM #Microscopy #dSTORM #Nanoimager #DiscoveryKit #TrainingKit #ExtraCellularVesicles #LipidNanoparticles #EMBL #EMBLEvents
Check out how Prof@doloresdivizio.bsky.social and her team at @cedars-sinai.bsky.social will use ONI’s #Nanoimager to explore #cancer progression. From #SuperResolution imaging of Large #Oncosomes to #LiquidBiopsy, they are pushing the boundaries of #CancerResearch.
www.youtube.com/watch?v=T9jn...
ONI is attending CanSEV, the first in-person meeting of the Canadian Society for Extracellular Vesicles
We are so proud to support the first ever in-person meeting of #CanSEV, the Canadian Society for #ExtraCellularVesicles! Find us at the The Neuro, Montreal, May 20-21 2025 and check out our latest offers in EV research!
#CanSEV2025 #EVProfiler2 #AutoEV #Nanoimager #AploScope #dSTORM #SuperResolution
ONI team will be at ELMI 2025 meeting in Heidelberg, 3-6 June 2025.
🔬🌟 Find us at the 25th international meeting of the European Light Microscopy Initiative ( #ELMI ), 3-6 June 2025, Heidelberg, Germany! #ELMI2025 here we come! 🌟🔬
#SuperResolution #microscopy #SMLM #Nanoimager #AploScope #Fluorescence #SingleMolecule #LifeSciences #dSTORM #Immunofluorescence
ONI's LNP Profiler demo at the University of Strathclyde.
ONI's LNP Profiler demo at the University of Strathclyde.
Thanks to Yvonne Perrie, Sarah Lindsay, and Jade Forrester, for hosting us at the @unistrathclyde.bsky.social. We loved showcasing our #Nanoimager, #LNPProfiler and #AutoLNP!
Want to learn more? Join our webinar hubs.li/Q03kbFdM0 or contact us pages.oni.bio/request-a-sa...
DNA-PAINT image of tubulin in green and mitochondria in magenta.
To celebrate #DNADay from last week, this #FluorescenceFriday we have a #DNAPAINT image of #Tubulin ( #cytoskeleton ) in green and the #mitochondria protein #Tomm20 in magenta, taken by ONI former scientist Dr Nina Jajčanin Jozić using the #Nanoimager with probes from @massivephotonics.bsky.social.
A collage of dSTORM images of single EVs taken with the Nanoimager.
🌟 Happy #ISEV2025! 🌟
🧬 We are very excited to see you all at booth P2 and hear all about your exciting #ExtraCellularVesicles #research! We will be there with the #Nanoimager, #AploFlow, #EVProfiler2 with #AutoEV and more. Don't miss out! 🔬
@isev.org
Find us at ISEV2025 for a celebration of EVs and EV research! We'll be there with #EVProfiler2, #AutoEV, #AploFlow and of course, the #Nanoimager!
Read the papers:
hubs.li/Q03hGjS50
hubs.li/Q03hGcpZ0
With it, they can detect α-synuclein, the protein that is involved in the pathology in PD, which is enriched in EVs from PD patients. To validate their assay's detection of rare EV subpopulations, they inspected them using #dSTORM on the #Nanoimager and confirmed that their assay is very sensitive.
Several methods were used to study these EVs, among them ONI's #EVProfiler with the #Nanoimager and the software #CODI. Here is one the main figures in the paper which demonstrates how Integrin-enriched EVs lead to thrombosis.
The text "Happy NanoDays! Celebrating nanoscience" next to a Nanoimager and a fluorescently labeled neuron.
#NanoDays is a week-long celebration of #NanoScience held between the Last weekend of March and the first weekend of April. We specialize in #SuperResolution #microscopy and celebrate nanotechnology every day. For NanoDays, we share some facts about one of our flagship products - our #Nanoimager!
A montage of super-resolution SMLM imaging of lipid nanoparticles, with and without RNA cargo and target ligand.
It's #FluorescenceFriday and we are particularly excited to share this beautiful montage of #LipidNanoParticles ( #LNPs), prepared with our latest #LNPProfiler and imaged with #AutoLNP on the #Nanoimager! LNPs gained massive popularity lately, thanks to their transformative effect on #DrugDelivery.
#Biopharma #mRNA #GeneEditing #DrugDelivery #SuperResolution #Nanoimager #Innovation #ONI #AploScope #LNP #DrugDiscovery #VaccineDevelopment #DrugDelivery #Liposomes #GeneTherapy #DrugDevelopment #Innovation #Biotechnology #Biotech #PrecisionMedicine #ProductLaunch #MachineLearning
We had a great time in the practical #SuperResolution workshop with @evcorefacilty.bsky.social in Marburg last week. We are thrilled that so many people came to learn how #SMLM on the #Nanoimager can take their #research forward, especially in fields like #CellBiology and #ExtraCellularVesicles.
Now it’s hands-on time! First #ExtracellularVesicles samples are being acquired & analyzed live. Get up close with the #Nanoimager and see the action unfold! 🔬 #EVs @oni-bio.bsky.social
Greetings of Happy Holi from ONI. The image shows captures of individual extracellular vesicles in vibrant colors, resembling the colored powders that are typical to this festival.
Happy Holi from all of us at ONI! We take this day to celebrate the beauty and the colors of the natural world around us.
The image here is a collage of single #ExtracellularVesicles (EVs) that were stained using our #EVProfiler2 kit and imaged on the #Nanoimager with #AutoEV.
#FluorescenceFriday
Focus on new exciting biological questions without worrying about the hardware and software that makes it possible 🚀
Explore how Aplo Scope can transform your research by watching our free webinar: hubs.li/Q039FQCS0
#lifesciences #biotech #SMLM #innovation #Nanoimager #CellBiology #Biophysics
We are excited about this use of our #Nanoimager for innovative technologies. It is truly inspiring to be able to see what used to be hidden until quite recently. Congratulations to this creative team, we cannot wait to see where will your curiosity take you next!
Read the paper: hubs.li/Q0391jM30
This work, which was led by PhD student Marrit Tholen (in the image here with the #Nanoimager!) was published in the journal Communications Biology from Nature Portfolio.
🎨 ONI and @massivephotonics.bsky.social offer a DNA-PAINT reagent kit, optimized for the #Nanoimager and for #AploScope. Here we have a DNA-PAINT image of the #cytoskeleton #protein #vimentin, prepared with the kit and imaged with the Aplo Scope. 🔬
Read more about DNA-PAINT: hubs.li/Q038ZBWL0 🌟
They used a number of approaches, among them using the #Nanoimager for the #SuperResolution #SMLM method #DNAPAINT, to pin-point the precise cellular localization of FMRP, as well as its binding partners.
