The project “Modification of the #vimentin filament network regulating #cellmechanics and #matrixremodeling in #3Dpulmonaryfibrosismodels” has been funded in OPUS 29 NCN. Congratulations to Joanna Zemla, who will lead this project. #IFJPAN. #NCN #OPUS29 #PulmonaryFibrosis
My first postdoc preprint is out!
Upon starvation, the Vimentin IFs network rapidly compacts (in <15 min!) to "cage" ER-Endosome membrane contact sites. This spatial confinement is crucial for autophagosome biogenesis.
www.biorxiv.org/content/10.6...
#CellBiology #Autophagy #Vimentin
@vgelfand.bsky.social et al. use single-particle tracking to show #vimentin intermediate filaments display active movement throughout the cell, w/ individual filaments w/in a bundle moving independently rupress.org/jcb/article/...
📕 Intermediate Filaments collection: rupress.org/jcb/collecti...
Pasolli, @joycemeiri.bsky.social, Akhmanova et al. describe tools to acutely relocate #vimentin intermediate filaments by inducibly coupling them to microtubule motors. rupress.org/jcb/article/...
📕 In our Intermediate Filaments collection: rupress.org/jcb/collecti...
#Euro-IF
🍹This Perspective discusses recent insights into #vimentin filament structure and function, as well as emerging findings that point to a role in #tumor invasion in #mesenchymal cells analogous to embryonic development and wound healing.
👉https://rdcu.be/eCOQp
bit.ly/423dC3c
Optogenetic and chemical genetic tools for rapid repositioning of #vimentin intermediate filaments. New tools developed by Milena Pasolli, Joyce Meiring @joycemeiri.bsky.social, Anna Akhmanova and colleagues @utrechtuniversity.bsky.social: rupress.org/jcb/article/...
@gijsjekoenderink.bsky.social
In @jcb.org, Pasolli, Meiring, Akhmanova et al. @utrechtuniversity.bsky.social describe tools to acutely relocate #vimentin intermediate filaments by inducibly coupling them to microtubule motors. rupress.org/jcb/article/...
@joycemeiri.bsky.social @gijsjekoenderink.bsky.social
#Cytoskeleton
New: Pasolli, Meiring, Akhmanova et al. @utrechtuniversity.bsky.social describe tools to acutely relocate #vimentin intermediate filaments by inducibly coupling them to microtubule motors. rupress.org/jcb/article/...
@joycemeiri.bsky.social @gijsjekoenderink.bsky.social
#Technology #Cytoskeleton
The unexpected structure & dynamics of #vimentin networks. Komal Bhattacharyya & Stefan Klumpp discuss new work from Renganathan et al. (rupress.org/jcb/article/...) that provides unprecedented detail of the intermediate filament network in cells rupress.org/jcb/article/...
#Cytoskeleton
Excited to see our work on #vimentin dynamics and organization sparking interest among researchers! Delighted to have it featured in @jcb.org with an insightful commentary by Prof. Stepen Klumpp & Komal Bhattacharyya. Grateful for their perspectives on our research!
Spotlight from Bhattacharyya and Klumpp: Combining two powerful imaging techniques, Renganathan et al. (rupress.org/jcb/article/...) provide unprecedented detail of the intermediate filament network in cells. rupress.org/jcb/article/...
#Cytoskeleton #Vimentin
We are hosting Dr. Miguel Cruz from Baylor College of Medicine in our Friday Seminar Series! 🩸
📅 March 21, 2025 @ 11 EST
🗺️ Mary Ellen Jones @ UNC
👨🏫 "Extracellular Vimentin and Thrombosis"
Host: Matt Flick, PhD @fib390-396a.bsky.social
#vimentin #thrombosis
#Vimentin filament transport and organization revealed by single-particle tracking and 3D FIB-SEM. New study from Bhuvanasundar Renganathan (@buvansr.bsky.social), Andrew Moor (@aaandmoore.bsky.social), Vladimir Gelfand (@vgelfand.bsky.social) and colleagues: rupress.org/jcb/article/...
#Microscopy
Excited to share our work @jcb.org !!! We believe this is a key piece in the #vimentin & #IntermediateFilament field, highlighting its dynamic nature. This opens the door for exploring crosstalk with other cytoskeletal components!
Challenging the view on #vimentin! our latest work shows VIF is an active, dynamic filament loosely held together
rupress.org/jcb/article/...
Thanks to @vgelfand.bsky.social @aaandmoore.bsky.social @nu-bsa.bsky.social @hhmijanelia.bsky.social @jcb.org #NUCDB #nikon #CrestOptics #livecellimaging
Renganathan, Moor, @vgelfand.bsky.social et al. use single-particle tracking to show that #vimentin intermediate filaments display active movement throughout the cell, with individual filaments within a bundle moving independently rupress.org/jcb/article/...
#Cytoskeleton #Microscopy
🎨 ONI and @massivephotonics.bsky.social offer a DNA-PAINT reagent kit, optimized for the #Nanoimager and for #AploScope. Here we have a DNA-PAINT image of the #cytoskeleton #protein #vimentin, prepared with the kit and imaged with the Aplo Scope. 🔬
Read more about DNA-PAINT: hubs.li/Q038ZBWL0 🌟
A DNA-PAINT image of vimentin, taken with the Aplo Scope.
A #microscope's large Field of View allows to record more data in each #imaging session.
Here we have a #DNAPAINT image of #vimentin taken with the #AploScopem which has a Field of View of 110 x 110 µm. Together with the #SMLM imaging provides an exceptional level of details.
