This study shows that RAB26 promotes #ProstateCancer (PCa) cell growth while inhibiting #apoptosis, regulating #Epithelial - #mesenchymal transition and stemness, and offering potential targets for targeted therapy in PCa. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...

Vimentin intermediate filaments as structural and mechanical coordinators of mesenchymal cells - Nature Cell Biology This Perspective presents recent insights into vimentin filament structure and function and discusses emerging findings that point to a role in tumour invasion in mesenchymal cells analogous to embryo...

🍹This Perspective discusses recent insights into #vimentin filament structure and function, as well as emerging findings that point to a role in #tumor invasion in #mesenchymal cells analogous to embryonic development and wound healing.
👉https://rdcu.be/eCOQp

bit.ly/423dC3c

#Mesenchymal stromal cells (MSCs) → mediate repair. #Obesity impairs MSC functionality → #inflammation. bit.ly/4mEqzZJ

Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...

Happy to announce our preprint going live on BioRxiv! Interested in what’s happening to your fibroblasts’ transcriptomic phenotype once it’s in culture? Look no further!

www.biorxiv.org/content/10.1...

@denklab.bsky.social
#fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal

“GLOBAL SHOWCASE” with “Unlock Scalable MSC and EV Production,” Ravenska Wagey, PhD; May 9, 10:15–10:30 a.m.

Tomorrow, learn about strategies for efficient, scalable expansion of #mesenchymal stem cells (MSCs) in animal component-free culture systems to support #CellTherapy and regenerative medicine applications. #ISCT2025

bit.ly/4iYVAoB
@isctglobal.bsky.social

Neuroscientists Unveil Digital 'Translator' for Brain Studies | Newswise UCLA Health researchers have helped to develop a new digital toolbox to create a “common language” for brain network studies, potentially accelerating new discoveries and treatments for neurological a...

Neuroscientists Unveil Digital 'Translator' for Brain Studies
www.newswise.com/articles/neu...
#CD47 #mesenchymal #fracturerepair #bonefracture #inflammation #translator #studies

In a paper published in the International Journal of Oral Science on February 1, 2025 researchers from Sichuan University introduced a novel approach to improve exosome efficacy for TMJOA treatment.
#Cell signalling #Mesenchymal stem cells
Details: doi.org/10.1038/s41368-024-00329-5

During "Epithelial-to-Mesenchymal Transition" (EMT), #epithelial cells 🟠 lose cellular adhesion & gain #mesenchymal traits 🟩

@onamy.bsky.social & team find that ribosomal composition changes & ribosomal protein #RPL36A #overexpression promotes EMT

👇Our proposed @pnas.org #coverart summarizes this