Overexpression of high affinity Type I adenosine receptors promotes the growth of uterine leiomyomas Abstract. Leiomyomas are benign proliferations of uterine smooth muscle found in 60% of women. A spatial redistribution of ecto-5’-nucleotidase (CD73, NT5E

In this article, the authors explored the mechanisms by which altered extracellular adenosine levels contribute to fibroids growth, and identified the #overexpression of ADORA1 receptor in leiomyoma.
academic.oup.com/molehr/advan...

During "Epithelial-to-Mesenchymal Transition" (EMT), #epithelial cells 🟠 lose cellular adhesion & gain #mesenchymal traits 🟩

@onamy.bsky.social & team find that ribosomal composition changes & ribosomal protein #RPL36A #overexpression promotes EMT

👇Our proposed @pnas.org #coverart summarizes this