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#
Hashtag
#ParaxialMesoderm
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Is CoA a problem because an over-constrictive (flow-sensitive) SMC subpopulation of CNC origin has invaded the aortic zone, which is supposed to be populated by mesodermal SMCs?😁

Is CoA a problem because an over-constrictive (flow-sensitive) SMC subpopulation of CNC origin has invaded the aortic zone, which is supposed to be populated by mesodermal SMCs?😁

#CoarctationOfAorta
A developmental problem of #SmoothMuscleCell #BoundaryFormation?😃

"a border is formed at the interface b/w #CardiacNeuralCrest- derived SMCs in the 6th #PharyngealArchArtery & #ParaxialMesoderm -derived SMCs in the dorsal aorta"

#JDBMDPI 2025
www.mdpi.com/2221-3759/13...

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Post image

#Pericyte progenitors #Zebrafish🐟

nkx3.1 marks early🧠 pericyte progenitor from #ParaxialMesoderm & #NeuralCrest

Ablating nkx3.1+ progeny 24~48hpf➡️
⏬Pericyte
Arterial mispatterning
⏫🧠hemorrhage

1/3🧵
Sarah Childs lab bioRxiv 2023
www.biorxiv.org/content/10.1...

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