Interesting talk by Karlijn Meerman at #KNCVMCCB2026. She talked about her #PhD research in the @feringalab.bsky.social about making photoswitchable cyclic peptides in collaboration with Nathaniel Martin of our @led3hub.bsky.social.

#ChemSky #ChemBio #Peptides #PhotoSwitch

💡 Ready to light up your project? 
Burkhard König et al. explain the important terminology and discuss the synthesis, switching mechanisms & properties of 7 #photoswitch classes. Check out the full tutorial review & start switching!
🔗 https://tinyurl.com/36tdmj92
@uniregensburg.bsky.social
#BJOC 💎🔓

Greenfield Group — University of St Andrews

📢Our team will be advertising a number of fully-funded positions in the coming months (new photoswitch-based projects)💡🚨 Applicants from the 🇪🇺 and 🇨🇳 are encouraged. More info will be coming soon and advertised on our website imineswitch.com
#photoswitch #imine

Re-ver-si-ble CPL inversion promoted by light and heat!
This collaborative work between the @feringalab.bsky.social and our group, the PulSAr team @univangers.bsky.social, is now online on ChemArXiv.
Special congrats to Louis and Eric!

chemrxiv.org/engage/chemr...

#motor #PDI #PBI #Photoswitch

Photoresponsive molecular tweezers modulate Taspase 1 activity Light serves as an exceptional stimulus for the precise spatiotemporal regulation of protein activity and protein–protein interactions. Here, we introduce a light-responsive supramolecular ligand syst...

🔦 Light Switch for Proteases💡
Controlling proteins with a light dimmer: This allows protein functions to be precisely modulated. Read more here 👉 doi.org/10.1039/D5CB00069F #Photoswitch #Photoresponsive #Taspase1 #ProteinManipulation

Light‑Switchable Magnets with Hours‑Long Magnetic State Developed

A Prague research team created a light‑activated molecule that stays magnetic for over six hours and can be produced for about 1,000 Czech crowns per kilogram. Read more: getnews.me/light-switchable-magnets... #photoswitch #magnetism

📢New perspective on light responsive imine-based systems out now in @chemicalscience.rsc.org with @jiarongwu.bsky.social 💡🚨🔦 This is part of the 2025 Leading Investigators Collection, Thank you to the reviewers for input 🙏 #hot #photoswitch #imine imineswitch.com
doi.org/10.1039/D5SC...

Looking for a new photoreactor?

Check out @asynt.bsky.social’s extensive range of photochemistry platforms for both batch and flow methodologies.

www.asynt.com/products/pho...

#photochemistry #photocatalysis #photoswitch #chemsky #realtimechem

#chemsky
#photoswitch

“Clicked” Hydrazone Photoswitches The length of the linker connecting a photoswitch to a material significantly influences the latter’s properties, with “zero-length” linkers being ideal for optimal photomodulation. The 1,2,3-triazole...

Click chemistry is a powerful way to stitch molecules together — but in our new @jacs.acspublications.org paper bit.ly/4cNBqMK we find that not all triazoles are equal! When it comes to #photoswitch the 1,5-regioisomer (not from "click") surprisingly outperforms the classic 1,4🧪⚗️ #molswitch #chemsky

Rainer Herges and co-researchers from Kiel University @uni-kiel.de  synthesized N-acetyl diazocine derivatives via cross-coupling reaction: ➡️ www.beilstein-journals.org/bjoc/articles/21/36

#diazocine #photoisomerization #photoswitch
#BJOC 💎🔓

🧵9/9
Now I am looking forward to next-gen works photocontrolling membrane permeation of diverse other species & in live: from highly polar cargos hidden in known carriers, to macromolecules, to #thiol-mediated uptake (?!) - who knows?

#lipids & #photoswitch membranes: a match made in HEaVℕ

🧵8/n
& hats off to the lipid #photoswitch academics (@dirktrauner.bsky.social, Klaus Groschner, James Frank, Oleksandra Tiapko, @dbkonrad.bsky.social, @fuchtermatt.bsky.social, & more) for the chemistry that means you can now just buy photo #lipids from €€ndustry (Avanti etc) to try this at home :)

🧵2/n
To date, most biophyiscs work on ion photocurrents took a one-reagent approach: either photoswitching
(a) a specific ionophore's ion affinity, or
(b) a membrane constituent's general *ion* permeability.

=> time-consuming, low switchability, low currents.
#photoswitch #photopharmacology

some feeds that may be interesting for the photochem crowd:

#Photoswitch & friends: bsky.app/profile/trac...

#FluorescenceFriday: bsky.app/profile/trac...

#ChemBio & imaging probes:
bsky.app/profile/trac...

📯Chemical Biology Starter Pack ＃2: Probes Aficionadas👩‍🔬 go.bsky.app/DEjVGEn

as generalist ChemBio Pack ＃1
go.bsky.app/KLrTWoj is full

🚩Feed reposting #ChemBio: bsky.app/profile/trac...

🚩 #Photoswitch: bsky.app/profile/trac...

🚩 #FluorescenceFriday:
bsky.app/profile/trac...

#chemsky #realtimechem

📯📯Photopharmacology and Switches communities📯📯

Here is a Feed reposting #molswitch #photoswitch #photopharma

bsky.app/profile/did:...

#chemsky #chembio #scisky 🧪

Here is a Feed that reposts #molswitch #photoswitch #photopharma for tracking our community science posts - Ivan if you like it, please feel free to link it in the Pack description and add as a Recommended Feed

bsky.app/profile/did:...

#chemsky #chembio #scisky 🧪

Switching Sides: Regiochemistry and Functionalization Dictate the Photoswitching Properties of Imines You know what imine? Aryliminopyrazoles have demonstrated their suitability as photoswitches and in driving dynamic-covalent reactions out-of-equilibrium. However, the influence of their structure on...

💡If you find these improved imine-based photoswitches interesting, you can find an overview of their properties at the link below 👇, as well as the first crystal structure of a metastable Z-aldimine! TOC designed by @jiarongwu.bsky.social

#chemsky #photoswitch #imine

doi.org/10.1002/anie...

#research #photoswitch #MolecularMotors

Triptycene-Based Tripodal Molecular Platforms (Kaleta) - Chemistry – A European Journal: doi.org/10.1002/chem...

@iocbprague.bsky.social #CzechAcademyofSciences #charlesuniversity