Left: Intracortical intensity profiles were extracted at each vertex of infant structural MRI scans. Intensities were sampled at 12 equivolumetric intracortical surfaces, spanning from the pial boundary (blue) to the white matter boundary (yellow), capturing signal variations across cortical depths, defined as microstructure profiles. Top right: Systematic changes in profile shape with respect to (i) center of gravity and (ii) variance. To illustrate this relationship, all profiles (across participants and regions) were sorted according to the respective moment, then averaged within 100 bins. Bottom right: Parcel-wise central moment distributions mapped on the dHCP 40-week surface template (see S1 Data). Excluded regions (i.e., von Economo areas LA1, LA2, LC1, LC2, LC3, LD, and LE and the cortical wall) are shown in gray.
How do #prenatal & #postnatal periods shape the developing human #cortex? This study uses #neonatal MRI to show that time in the womb drives widespread, uniform maturation, whereas time after birth produces more region- & depth-specific changes across the cortex @plosbiology.org 🧪 plos.io/47o6rpk
