Precancerous niche remodelling dictates nascent tumour persistence - Nature A study investigating the emergence of squamous tumours in the upper gastrointestinal tract of the mouse shows that an initial tumour stress response triggers fibroblasts to remodel the underlyin...

#WeekendRead! #SmartTumor! #EveryCellIsAnImmuneCell! Amazing work @nature.com by @mariapalcolea.bsky.social Skrupskelyte, Rojo &co showing the stress response driven by nascent tumors induces a wound healing program in surrounding fibroblasts driving a #PreCancerousNiche that fosters tumorigenesis!