Replacement of a single residue in an antibody abolishes cognate antigen binding, as predicted by theoretical methods. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.018

🔗 Replacement of a single residue in an antibody abolishes cognate antigen binding, as predicted by theoretical methods. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#AntibodyEngineering #StructuralBiology #ProteinModeling #Biophysics #FTIR

TBM preferred to AlphaFold 3 for functional models of insect odorant receptors. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.08.028

🦟 Could smarter protein modeling unlock eco-friendly pest control?

🔗 TBM preferred to AlphaFold 3 for functional models of insect odorant receptors. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#StructuralBiology #ProteinModeling #AlphaFold

Researchers glimpse the inner workings of protein language models MIT researchers used sparse autoencoders to shed light on the inner workings of protein language models, an advance that could streamline the process of identifying new drugs or vaccine targets.

"Researchers glimpse the inner workings of #protein language models"

#AI #ProteinModeling #Science

news.mit.edu/2025/researc...

GitHub - Mikel-MG/CCfrag Contribute to Mikel-MG/CCfrag development by creating an account on GitHub.

PLUS: The CCfrag Python module for fragment-based coiled-coil modeling using #AlphaFold, is now available. Explore its capabilities and access the code here: github.com/Mikel-MG/CCf... #StructuralBiology #ProteinModeling

GitHub - KhondamirRustamov/AF-Multimer-cluster Contribute to KhondamirRustamov/AF-Multimer-cluster development by creating an account on GitHub.

PLUS: You can explore the AF-Multimer clustering pipeline, an #OpenSource tool designed to enhance #AlphaFold's ability to predict protein-protein interactions.

Access it here: github.com/KhondamirRus...

#StructuralBiology #ProteinModeling

MassiveFold advances protein structure prediction with efficient parallel processing Researchers developed MassiveFold, an enhanced AlphaFold version optimized for parallel processing, which accelerates protein structure predictions from months to hours while increasing structural div...

MassiveFold advances protein structure prediction with efficient parallel processing 🔬🚀📊 www.news-medical.net/news/2024111... #ProteinStructure #AlphaFold #A #Science #MassiveFold #ComputationalBiology #ProteinModeling #Bioinformatics #DrugDiscovery