Targeting CAPON to modulate the CAPON–NOS Axis: a computational approach. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.001

🔗 Targeting CAPON to modulate the CAPON–NOS Axis: a computational approach. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#DrugDiscovery #ComputationalBiology #AlzheimersResearch #Neuroscience #ProteinProteinInteractions #VirtualScreening

📝 Online now - the Review "PTMs as molecular encoders: reprogramming chaperones into epichaperomes for network control in disease" from @chiosislabmskcc.bsky.social et al.

#ProteinProteinInteractions #ProteinNetworks #ChaperoneReprogramming

Read it here 👉 authors.elsevier.com/sd/article/S...

📣 Online now - the Feature Review "Exploring non-degrading molecular glues for protein-protein interaction" from Jian Zhang, Wenchao Lu, and co.

#ProteinProteinInteractions #MolecularGlues #ChemicallyInducedProximity #DrugDiscovery

Read it here 👉 authors.elsevier.com/a/1leHv3S6Gf...

Long-read sequencing to detect full-length protein–protein interactions. #LongRead #Sequencing #ProteinProteinInteractions #PPi #ScientificReports
www.nature.com/articles/s41...

Design of intrinsically disordered region binding proteins Intrinsically disordered proteins and peptides play key roles in biology, but a lack of defined structures and high variability in sequence and conformational preferences have made targeting such syst...

New approach for designing proteins that bind intrinsically disordered protein regions ➡️ www.science.org/doi/10.1126/...
#IDRs #ProteinProteinInteractions

DEADLINE REMINDER June 15th for Early Registration Fee / Abstract Submission: 8th Int'l Conference on #Molecular Perspectives in #ProteinProteinInteractions #PPI from Oct. 17-22 in #Chania #Crete www.aegeanconferences.org/src/App/conf...

Ligand recognition by 14-3-3 proteins: is #phosphorylation required?

➡️bit.ly/43jJLFq

#ProteinProteinInteractions

Extracellular proximal interaction profiling by cell surface–targeted TurboID reveals LDLR as a partner of liganded EGFR A modified form of TurboID identifies extracellular interactions between transmembrane proteins.

In a new #ScienceSignaling study, researchers introduce extracellular #TurboID, a refinement of the popular proteomics tool that interrogates #ProteinProteinInteractions on the exterior cell membrane, and characterize interactions between #EGFR and #LDLR. scim.ag/3DgfJr9

Using AlphaFold Multimer to discover interkingdom protein–protein interactions The prediction of structure of protein complexes with artificial intelligence is making a deep impact in plant science. Here, we share our experiences on using AlphaFold Multimer on a computing clust...

📜 Using AlphaFold Multimer to discover interkingdom protein–protein interactions

🧑‍🔬 Felix Homma, Joy Lyu, Renier A. L. van der Hoorn

📔 The Plant Journal

🔗 onlinelibrary.wiley.com/doi/10.1111/...

#️⃣ #PlantScience #AlphaFold #ProteinProteinInteractions #PlantProteomics