Nef stabilizes actin to prevent HIV-1 sensing by RIG-I-like receptors Nature Communications - The study shows that the HIV-1 Nef protein stabilizes actin, thereby preventing R12C release and priming of RIG-I–like receptors. HIV-1 containing a mutant Nef unable...

Excited to share our new paper and a new Nef function !

rdcu.be/eTFJh

Thanks to everyone involved!
@caterinaprelli.bsky.social
@sparrerlab.bsky.social

#hiv #Nef #innateimmunity #sensing #rlr #research

Of course, I wonder, what #MDA5 is doing in all of this? But maybe thats for another paper... Anyway, a great article, I highly recommend this to the #virus #RNA #innateimmunity #RIGI #RLR peoples!

Nächster Halt Altenbeken - für #derFahrrad und mich geht es heute nach Detmold (ohne Hermann) und von da aus über die (angepasste) Berg-Etappe der #RömerLippeRoute #RLR nach Paderborn. 46k mit "nur" 310 Höhenmeter - ich habe die eigentliche Strecke etwas verlängert und konnte so Höhe rausnehmen.

For artists who have an account on Art Fight, RLR is back again on the site this July with new characters! Last year, it was just the three rascals, but now we have Gigi and Mrs. Bakery added!

All RLR characters have a "❤︎" beside their name! :D
artfight.net/~iamcreative...

#rlr #artfight2025

Pünktlich zum bevorstehenden #STADTRADELN Start wurden die Radwegweiser in 🐍 z.T. erneuert und korrigiert. Zusätzlich wurde der Verlauf der #RömerLippeRoute angepasst. Diese führt nun sinnvollerweise durch die Ortsmitte 🍕🍻🍔🍰. #senneteutoegge #RLR #Radfahren #Lippe

Join the Rowdy Little Rascals Discord Server! Check out the Rowdy Little Rascals community on Discord - hang out with 8 other members and enjoy free voice and text chat.

Hello!!!

Rowdy Little Rascals now has a brand new discord server where I will share updates for the animation series! (Better late than never!)

Join here today!
discord.gg/k2x2f2apDZ

#discord #rowdylittlerascals #rlr #animationseries #animation #cartoon

Tune in to our new RLR podcast episode out now! 🎧

Join Rabih and Prof Reza as they tackle 2 cases of abdominal distention.

Listen now using the link ➡️ clinicalproblemsolving.com/2025/03/03/e...

#MedSky #RLR

More snippets of my animated series, Rowdy Little Rascals Episode 9!! Ms. Winnie is currently stuck eating caramel bites :(((((

VA: Kelly Ulleanne ✨

Link to the episode playlist!
youtube.com/playlist?lis...

tags: #rowdylittlerascals #indieanimation #cartoonanimation #rlr #youtube

Happy Indie Animation Day!
I present to you a clip from Episode 9 of my animated series, Rowdy Little Rascals! (1/2)

VA: SoftMushroomBaby

Here's a link to the series:
www.youtube.com/playlist?lis...

Tags: #indieanimationday #rowdylittlerascals #animation #animatedseries #2danimation #rlr #youtube

Last post of the year here goes to Trixx themselves!
Happy Birthday Trixx!! 🎉

tags:
#rowdylittlerascals #birthday #krita #artwork #cartoonart #chocolatepudding #rlr

My animated series Rowdy Little Rascals has just wrapped up production for Episodes 5-8! :)

This little cartoon has come so far. 🥹

See the full playlist here:
youtube.com/playlist?lis...
--
tags: #rowdylittlerascals #rlr #animationseries #cartoon #animation #cartoonart #digitalart #cute #colorful

Nice overview about the complex regulation of #RIGI #RLR #signaling with a focus on the events happening at the mitochondrion. #antiviralresponse #interferon #innateimmunity #virus

www.frontiersin.org/articles/10.3389/fcell.2...