The last manuscript from the lab is out there!!! We found that #RNAmodifications are involved in the #antiviralresponse in the context of #celiacdisease suggesting potential therapeutic interventions.
rdcu.be/eYn7S
New #paper out by Volker Lohmann’s lab @CiidHeidelberg on the #antiviralresponse of our cells towards #hepatitis A and C (#HCV) virus infection! Great collaborative work within @TRR179_2 w/ contributions of @BartenschlagLab, @CancerInflam and...
☝️#innateimmunity #antiviralresponse #RIGI #interferon #virology #cytokines @CytokineSociety
Way too often overlooked by us simplistic cell biologists: alternative splicing! This plays a role *everywhere*, including #signaling in the #antiviralresponse. Huo-Chieh Liao and Mariano Garcia-Blanco took the effort summarizing current...
This is definitely going to be my #1 overview article for the everything related to RNA sensing in antiviral immunity for the next few years! Awesome work by Michaela Gack and GuanQunLiu @CCLRI!!
#antiviralresponse #cytokines #interferon...
Wow, Chris @cssince73_chris @Sullivan_Lab, beautiful story! I know you’ve been on to this for quite a while, but this story was totally worth it! Congrats to everybody involved!
#RIG_I #antiviralresponse...
Don’t miss out on David Zander presenting the results of his impressive 1.5 years MD thesis in our lab! Today, 11:45-13:45 PST (20:45 UTC+1) @CytokineSociety #cytokines2020!
LT203: Cell-intrinsic #antiviralresponse in cell death induction upon DNA damage
https://bitly.com/3jSV7pA
Nice overview about the complex regulation of #RIGI #RLR #signaling with a focus on the events happening at the mitochondrion. #antiviralresponse #interferon #innateimmunity #virus
www.frontiersin.org/articles/10.3389/fcell.2...
And another congrats– this time to my former colleague and good friend Katharina (KEN) from the @UW_GaleLab! Super-thorough comparison of different #Zika strains and their sensitivity to the #antiviralresponse! #virology #innateimmunity...
Thinking about the nice story by @TheHornerLab on the role of m6A in #flaviviridae / #flavivirus lifecycles seemingly independent from the #antiviralresponse: www.sciencedirect.com/science/article/pii/S193...
And, lastly, great review on cellular m6A machinery:...
Retweeting as the deadline approaches! Talented #biology, #immunology, #virology students out there, apply! #PhDpositions available at @DKFZ, including @TheBinderLab!
Deadline: Januar 5th 2020!
#virology #innateimmunity #antiviralresponse #inflammation #cancer
If you ever wondered (as we do #trr179) how chronic viral #infection, particularly in the #liver, impacts on immune function, the @Bergthalerlab has some interesting findings! #immunometabolism #Immunology #innateimmunity #antiviralresponse #virology
...
Interesting and potentially important in #antiviralresponse: helicase ZNFX1 is a dsRNA sensor #signaling through MAVS (in the absence of CARDs). At first glance, I'm not convinced about it being independent and upstream of #RIG_I. #innateimmunity #virology
https://rdcu.be/bWrTQ
Beautiful work by @BoulantLab! TLR3 localisation helps gut epithelium keeping a relaxed attitude towards the microbiome, but remaining alert for pathogenic insult! #antiviralresponse #innateimmunity #virology #virus
Quick read:...
Beautiful overview of the Interplay between #dengue virus and human #innateimmunity by my former colleague Laurent Chatel-Chaix and colleagues from @inrsciences ! #flavivirus #interferon #antiviralresponse #signaling #vaccines
https://www.mdpi.com/549706
Fantastic review on Filament-like Assemblies of Intracellular Nucleic Acid Sensors by Sun Hur and Cris Cadena! Finally, our observation of #RIG_I forming massive oligomers on long dsRNA enters mainstream. #antiviralresponse #signaling...
Super talk by Thomas Decker on ISGF3 and other STAT/IRF9 transcription factors. Also new aspects on TF cooperativity at promoters- some ISGs are strongly dependent on p38 MAPK activity, while others are not at all! @cytokines2019 #antiviralresponse #signalling #interferon
Great talk, @dittmannlab! Let‘s try to now find out the details on what‘s going on with #ELF1- we‘ll be happy to contribute! #cytokines2019 #antiviralresponse #interferon
@Vladimir_Magalh presenting our story of DAPK1/2/3 inhibiting RIG-I #signalling in the #antiviralresponse. Humbling venue in #Hofburg #Vienna, well done @Vladimir_Magalh! #cytokines2019
Our friend Nadine Gillich giving a discussion-inspiring talk on LGP2‘s sole in RNA sensing in general and Hepatitis delta virus infection in particular. #cytokines2019 #virology #antiviralresponse
