#Radiosensitivity hashtag - Bluesky

@currentmedscience.bsky.social

2 months ago

TOPK Inhibition Enhances the Sensitivity of Colorectal Cancer Cells to Radiotherapy by Reducing the DNA Damage Response

TOPK was overexpressed in patients with moderately to poorly differentiated CRC receiving #Radiotherapy, while its knockdown significantly enhanced the #Radiosensitivity of CRC cells by reducing the #DNAdamageResponse.
Read more: doi.org/10.1007/s115...

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Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

7 months ago

A novel ENPP1+ phenotype confers radioresistance by enhancing #DNADamageRepair (DDR), while its inhibition impairs DDR, thereby enhancing #Radiosensitivity and antitumor immune responses in #TNBC. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

7 months ago

A novel ENPP1+ phenotype confers radioresistance by enhancing #DNADamageRepair (DDR), while its inhibition impairs DDR, thereby enhancing #Radiosensitivity and antitumor immune responses in #TNBC. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

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Chaz Hong MD PhD

@chazhong.bsky.social

1 year ago

Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types Scientific Reports - Inhibition of GPR68 induces ferroptosis and radiosensitivity in diverse cancer cell types

Hong lab is on a roll in 2025! Our latest paper showing GPR68 inhibition induces #ferroptosis & #radiosensitivity in diverse cancer cell types like lung & pancreatic cancer cells. Therapeutic synergy with radiation therapy. #SpartansWill rdcu.be/d8rGf

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