The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging - Nature Medicine The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic proteomic…

At IPI, we’re building #antibodies to explore neurodegenerative targets, including #Ephrin & #Semaphorin. That’s why we’re excited by a landmark data set from @neuroproteome.bsky.social revealing #proteomic signatures in Alzheimer’s, Parkinson’s & more.

Take a look! www.nature.com/articles/s41...

The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging - Nature Medicine The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic proteomic…

The @neuroproteome.bsky.social has released 250M protein measurements from 35K+ samples, revealing #proteomic signatures in Alzheimer’s, Parkinson’s & more. At IPI, we’re building #antibodies to explore some of the targets, including #Ephrin & #Semaphorin. Read more: www.nature.com/articles/s41...

#Semaphorin 5A-#Glycosaminoglycan/GAG interaction ⏫PlexinA2-dependent dentate progenitor cell proliferation (not dendritic spines) in subgranular zone P14🐭

#HeparanSulfate >>#ChondroitinSulfate

#MassPhotometry➡️Heparin:Sema4A 4:1 oligomerization

#NatureComms 2024
www.nature.com/articles/s41...