LOF Slc35a2 in oligodendrocytes results in severe hypomyelination, a reduction of oligodendrocytes, and reactive gliosis.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #hypomyelination #malformations #corticaldevelopment #MOGHE #Slc35a2

📖 Read more: [https://doi.org/10.1007/s00401-025-02858-7]

#Neuroscience #EpilepsyResearch #Neuropathology #BrainDisorders #SLC35A2 #MOGHE

Welcome to Bluesky @katjakobow.bsky.social 🤩
I have added you to the starter pack on rare genetic epilepsies 🧠🧬
#FCDs #Epigenetics #MOGHE #SLC35A2