Our new work in @embojournal.org ! 🎉

PARP7 creates an ADP-ribosyl degron on chromatin-bound AR, leading to DTX2-mediated degradation and negative feedback in androgen signaling in prostate cancer.

Full: www.embopress.org/doi/full/10....

#ProstateCancer #PARP7 #AndrogenReceptor #TheEMBOJournal