Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

Check out the final version of this insightful work by Claire Masson and our long-lasting collaborators #EFS #UMR1255.

Very glad to be part of it with @naelosmani.bsky.social and kudos to @elife.bsky.social for a very transparent publishing process.

doi.org/10.7554/eLif...

❓ What makes #platelets sticky ?
👉 Integrins (among others) !
❓Can we generate a mouse model with NO integrins on #platelets ?
👉 Our collaborators #umr1255 #EFS had, and it is unique !❓What is the impact on #hemostasis, #thrombosis & #metastasis
👉 Massive in some instances, significant in others !