Function 🔙 #TBT: The #WarburgEffect has puzzled scientists for ~100 years. This study offered a new quantitative explanation of #AerobicGlycolysis in #cancer metabolism—and proposed a framework for ATP synthesis and metabolite recycling. 10.1093/function/zqae008
lncRNA ADAMTS9-AS2/let-7a-5p axis regulates metabolic reprogramming by targeting HK2 in oral submucous fibrosis-associated oral squamous cell carcinoma
The ADAMTS9-AS2/let-7a-5p axis modulates #MetabolicReprogramming in OSCC cells by suppressing #AerobicGlycolysis via targeting hexokinase 2 (HK2) to inhibit #OSCC progression. #WarburgEffect #OralCancer #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
Reducing glucose availability may impact cancer cell metabolism by limiting glycolysis and its byproducts. Low-carb diets, such as keto, reduce fermentable sources and are worth exploring
Learn more about it at www.cancereducation.net
#CancerEducation #WarburgEffect #CancerMetabolism
As tumors grow, abnormal blood vessel formation leads to hypoxia (low oxygen). This forces cancer cells to rely on glycolysis instead of oxidative phosphorylation, contributing to the Warburg Effect.
Learn more about it at www.cancereducation.net
#CancerEducation #WarburgEffect #Hypoxia
Mitochondria, the “powerhouses of the cell,” are crucial for respiration, but many cancer types show mitochondrial dysfunction, which may push cells toward glycolysis instead of oxidative phosphorylation.
Learn more about it at www.cancereducation.net
#WarburgEffect #Mitochondria #CancerEducaton
ICYMI: To celebrate 100+ years of the #WarburgEffect, editors from across Springer Nature put together a collection of clinical, translational and preclinical studies as well as commentaries of #CancerMetabolism research. www.nature.com/collections/... @natureportfolio.bsky.social
The Aldehyde Hypothesis | Heran Darwin
youtu.be/zLkq6a_W1nE?...
uploaded today
#ALDH2 #NitricOxide #Immunology #malondialdehyde #methylgyoxal #metabolism #WarburgEffect #Immunometabolism